Accéder au contenu
Merck
  • Surface characterization and osteoblast response to a functionally graded hydroxyapatite/fluoro-hydroxyapatite/titanium oxide coating on titanium surface by sol-gel method.

Surface characterization and osteoblast response to a functionally graded hydroxyapatite/fluoro-hydroxyapatite/titanium oxide coating on titanium surface by sol-gel method.

Cell proliferation (2014-04-18)
G He, B Guo, H Wang, C Liang, L Ye, Y Lin, X Cai
RÉSUMÉ

To improve efficacy of current titanium and its alloys, in bioactivity and speed of osseointegration, of orthopaedic implants. A novel triple-layered functional graded coating, consisting of a porous hydroxyapatite (HA) outermost layer, fluoro-HA (FHA) intermediate layer and titanium oxide (TiO2 ) innermost layer, was created on a titanium substrate by a multistep sol-gel method. X-ray diffraction analysis showed TiO2 anatase and apatite crystallization in the coating. Morphological analysis performed by scanning electron microscopy showed excellent bonding between coating and substrate, with a thickness of ~2 μm. Scratch testing found favourable adhesion strength of the composite coating. In addition, optical microscope images suggested good biocompatibility. Considering thet in vitro cell response, osteoblasts on the coating exhibited higher cell proliferation and ALP activity compared to pure titanium and HA coating, and demonstrated excellent coating bioactivity. Current results indicated that the novel TiO2 /FHA/HA coating has promising clinical applications in orthopaedic and dental implantation.

MATÉRIAUX
Référence du produit
Marque
Description du produit

Sigma-Aldrich
Oxyde de titane(IV), nanopowder, 21 nm primary particle size (TEM), ≥99.5% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), anatase, nanopowder, <25 nm particle size, 99.7% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), anatase, powder, 99.8% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), ReagentPlus®, ≥99%
Sigma-Aldrich
Titanium(IV) oxide, rutile, powder, <5 μm, ≥99.9% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), anatase, powder, −325 mesh, ≥99% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, rutile, nanopowder, <100 nm particle size, 99.5% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, mixture of rutile and anatase, nanopowder, <100 nm particle size (BET), 99.5% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.127 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, powder, <45 μm avg. part. size, 99.98% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.25 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, mixture of rutile and anatase, nanoparticles, <150 nm particle size (volume distribution, DLS), dispersion, 40 wt. % in H2O, 99.5% trace metals basis
Sigma-Aldrich
Titanium, powder, −100 mesh, 99.7% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, rutile, ≥99.98% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, rutile, 99.995% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), contains 1% Mn as dopant, nanopowder, <100 nm particle size (BET), ≥97%
Sigma-Aldrich
Titanium, sponge, 1-20 mm, 99.5% trace metals basis
Sigma-Aldrich
Titanium, wire, diam. 0.25 mm, 99.7% trace metals basis
Sigma-Aldrich
Oxyde de titane(IV), nanowires, diam. × L ~100 nm × 10 μm
Sigma-Aldrich
Titanium, foil, thickness 2.0 mm, 99.7% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.025 mm, 99.98% trace metals basis
Titanium, mesh, 100x100mm, nominal aperture 0.19mm, wire diameter 0.23mm, 60x60 wires/inch, open area 20%, twill weave
Sigma-Aldrich
Oxyde de titane(IV), nanowires, diam. × L ~10 nm × 10 μm
Sigma-Aldrich
Titanium, foil, thickness 0.5 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.995% trace metals basis
Sigma-Aldrich
Titanium, foil, thickness 0.127 mm, ≥99.99% trace metals basis
Titanium, mesh, 100x100mm, nominal aperture 4.3mm, wire diameter 1.5mm, 4.4x4.4 wires/inch, open area 94%, platinized diamond mesh
Sigma-Aldrich
Titanium, wire, diam. 1.0 mm, 99.99% trace metals basis
Sigma-Aldrich
Titanium(IV) oxide, rutile, <001>, (single crystal substrate), ≥99.9% trace metals basis, L × W × thickness 10 mm × 10 mm × 0.5 mm
Sigma-Aldrich
Titanium, foil, thickness 0.25 mm, 99.99% trace metals basis