The stability of this material in solution at 4°C has not been determined. Following reconstitution, aliquot and freeze at -20°C for up to 3 months.
SML0545
CID 1067700
≥98% (HPLC)
Synonyme(s) :
2-(Benzoylcarbamothioylamino)-5,5-dimethyl-4,7-dihydrothieno[2,3-c]pyran-3-carboxylic acid, 2-[[(Benzoylamino)thioxomethyl]amino]-4,7-dihydro-5,5-dimethyl-5H-thieno[2,3-c]pyran-3-carboxylic acid, CID-1067700, CID1067700, SID57578339
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5 MG
128,00 €
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5 MG
128,00 €
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About This Item
Formule empirique (notation de Hill) :
C18H18N2O4S2
Numéro CAS:
Poids moléculaire :
390.48
Code UNSPSC :
12352200
Nomenclature NACRES :
NA.77
128,00 €
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Devis pour commande en gros
Produits recommandés
Niveau de qualité
Essai
≥98% (HPLC)
Forme
powder
Couleur
white to light brown
Solubilité
DMSO: 10 mg/mL, clear
Température de stockage
2-8°C
Chaîne SMILES
[s]1c2c(c(c1NC(=S)NC(=O)c3ccccc3)C(=O)O)CC(OC2)(C)C
InChI
1S/C18H18N2O4S2/c1-18(2)8-11-12(9-24-18)26-15(13(11)16(22)23)20-17(25)19-14(21)10-6-4-3-5-7-10/h3-7H,8-9H2,1-2H3,(H,22,23)(H2,19,20,21,25)
Clé InChI
ATSWBWHRHAQVFM-UHFFFAOYSA-N
Actions biochimiques/physiologiques
CID 1067700 antagonizes ras-related protein Rab-7 and reduces class switch DNA recombination (CSR) in B cells and survival of plasma cells.[1]
CID 1067700 is a potent and competitive inhibitor of Ras-related GTPases that potently binds to Rab7 nucleotide binding site.
CID 1067700 is a potent and competitive inhibitor of Ras-related GTPases.
Caractéristiques et avantages
This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
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A Remedy for Lupus through Restraining Rab7
How H I V.
Journal of Immunology, 197, 3749-3750 (2016)
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Lin Bai et al.
Cell death & disease, 12(4), 392-392 (2021-04-14)
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by motoneuron loss, for which there is currently no effective treatment. Statins, as inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) reductase, are used as drugs for treatment for a variety of disease such
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Glucosamine (GlcN), a dietary supplement widely utilized to promote joint health and effective in the treatment of osteoarthritis, is an effective macroautophagy/autophagy activator in vitro and in vivo. Previous studies have shown that autophagy is required for hepatitis B virus
Articles
Cyclic nucleotides like cAMP modulate cell function via PKA activation and ion channels.
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After resuspending 5 mg CID 1067700 in DMSO, should it still be stored at 4°C or should it be stored at -20°C?
1 answer-
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