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S4311

Sigma-Aldrich

L-Serine

98.5-101.0%, suitable for cell culture, non-animal source, meets EP, USP testing specifications

Synonyme(s) :

L Serine, (S)-2-Amino-3-hydroxypropionic acid

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25 G
135,00 €
100 G
282,00 €
1 KG
1 390,00 €

135,00 €


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Devis pour commande en gros

Sélectionner une taille de conditionnement

Changer de vue
25 G
135,00 €
100 G
282,00 €
1 KG
1 390,00 €

About This Item

Formule linéaire :
HOCH2CH(NH2)CO2H
Numéro CAS:
Poids moléculaire :
105.09
Beilstein:
1721404
Numéro CE :
Numéro MDL:
Code UNSPSC :
12352209
eCl@ss :
32160406
ID de substance PubChem :
Nomenclature NACRES :
NA.26

135,00 €


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Devis pour commande en gros

Nom du produit

L-Serine, from non-animal source, meets EP, USP testing specifications, suitable for cell culture, 98.5-101.0%

Source biologique

non-animal source

Agence

USP/NF
meets EP testing specifications
meets USP testing specifications

Essai

98.5-101.0%

Forme

powder

Technique(s)

cell culture | mammalian: suitable

Impuretés

endotoxin, tested

Couleur

white

Pf

222 °C (dec.) (lit.)

Solubilité

H2O: 50 mg/mL

Application(s)

pharmaceutical (small molecule)

Chaîne SMILES 

N[C@@H](CO)C(O)=O

InChI

1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1

Clé InChI

MTCFGRXMJLQNBG-REOHCLBHSA-N

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Application

L-Serine has been used as a supplement in a medium to culture Chinese hamster ovary TF 70R cell line and in mouse embryonic fibroblast (MEF)-media.[1][2]

Actions biochimiques/physiologiques

L-Serine is a non-essential amino acid that acts as a precursor for nucleotide synthesis. It has roles in the development and function of the central nervous system.[3]
Precursor of glycine by serine hydroxymethyltransferase.

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)


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Biotechnology (2012)
Abel Lajtha, Simo S. Oja, Pirjo Saransaari, Arne Schousboe
Handbook of Neurochemistry and Molecular Neurobiology: Amino Acids and Peptides in the Nervous System (2007)
Yurena Vivas-García et al.
Molecular cell, 77(1), 120-137 (2019-11-18)
Phenotypic and metabolic heterogeneity within tumors is a major barrier to effective cancer therapy. How metabolism is implicated in specific phenotypes and whether lineage-restricted mechanisms control key metabolic vulnerabilities remain poorly understood. In melanoma, downregulation of the lineage addiction oncogene
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Progress in neuro-psychopharmacology & biological psychiatry, 29(5), 767-769 (2005-06-09)
Several lines of evidence suggest that D-serine, an endogenous agonist of the glycine site on the NMDA receptors, might play a role in the pathophysiology of schizophrenia. The purpose of this study was to determine whether levels of D- and

Questions

1–2 of 2 Questions  
  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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