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MAK071

Sigma-Aldrich

Pyruvate Assay Kit

sufficient for 100 colorimetric or fluorometric tests

Synonyme(s) :

Assay Kit for Pyruvate Detection

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About This Item

Code UNSPSC :
12161503
Nomenclature NACRES :
NA.84

Utilisation

sufficient for 100 colorimetric or fluorometric tests

Méthode de détection

colorimetric
fluorometric

Maladie(s) pertinente(s)

gastrointestinal diseases; cancer

Température de stockage

−20°C

Informations sur le gène

human ... PKLR(5313) , PKM2(5315)
mouse ... PKLR(18770) , PKM2(18746)
rat ... PKLR(24651) , PKM2(25630)

Description générale

Pyruvate is a central molecule in metabolism that is used and synthesized through multiple metabolic pathways including glycolysis and the transamination of alanine. Pyruvate may be further oxidized in the citric acid cycle, converted to carbohydrates during gluconeogenesis, or reduced to lactate. High levels of pyruvate are associated with liver disease and genetic disorders. Pyruvate has also been used to stimulate metabolism leading to loss of body weight.

Adéquation

Suitable for measuring pyruvate concentration in various biological samples such as blood, tissues, and culture cells.

Principe

Pyruvate concentration is determined by a coupled enzyme assay, which results in a colorimetric (570 nm)/fluorometric (λex = 535/λem = 587 nm) product, proportional to the pyruvate present.

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Réf. du produit
Description
Tarif

Pictogrammes

Health hazard
GHS08

Mention d'avertissement

Danger

Mentions de danger

H317,H334,H412

Classification des risques

Aquatic Chronic 3 - Resp. Sens. 1 - Skin Sens. 1

Code de la classe de stockage

10 - Combustible liquids

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Lauren K Wareham et al.
Antioxidants & redox signaling, 24(17), 1013-1028 (2016-02-26)
Carbon monoxide is a respiratory poison and gaseous signaling molecule. Although CO-releasing molecules (CORMs) deliver CO with temporal and spatial specificity in mammals, and are proven antimicrobial agents, we do not understand the modes of CO toxicity. Our aim was
Changes in muscle cell metabolism and mechanotransduction are associated with myopathic phenotype in a mouse model of collagen VI deficiency.
De Palma S, et al.
PLoS ONE, 8(2), e56716-e56716 (2013)
Abstracts of the XVIth International Conference on Biological Inorganic Chemistry, July 22-26, 2013, Grenoble, France.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 19 Suppl 1, 1-696 (2014-03-13)
Xiaolong Zhang et al.
Biotechnology and bioengineering, 115(9), 2217-2231 (2018-06-14)
N-acetylneuraminic acid (NeuAc) is widely used as a nutraceutical for facilitating infant brain development, maintaining brain health, and enhancing immunity. Currently, NeuAc is mainly produced by extraction from egg yolk and milk, or via chemical synthesis. However, its low concentration
Carsten Esselun et al.
Oxidative medicine and cellular longevity, 2019, 1652609-1652609 (2019-12-25)
The Mediterranean plant Silybum marianum L., commonly known as milk thistle, has been used for centuries to treat liver disorders. The flavonolignan silibinin represents a natural antioxidant and the main bioactive ingredient of silymarin (silybin), a standard extract of its
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