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A5880

Sigma-Aldrich

D-Amphetamine hemisulfate salt

Synonyme(s) :

(+)-α-Methylphenethylamine hemisulfate salt, Dextroamphetamine hemisulfate salt

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About This Item

Formule empirique (notation de Hill):
C9H13N · 0.5 H2SO4
Numéro CAS:
51-63-8
Poids moléculaire :
184.25
Numéro CE :
200-111-6
Numéro MDL:
MFCD00069209
Code UNSPSC :
12352116
ID de substance PubChem :
24891028
Nomenclature NACRES :
NA.77

Forme

powder

Contrôle du médicament

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Solubilité

H2O: soluble
ethanol: soluble

Application(s)

forensics and toxicology

Chaîne SMILES 

OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2

InChI

1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)/t2*8-;/m00./s1

Clé InChI

PYHRZPFZZDCOPH-QXGOIDDHSA-N

Informations sur le gène

human ... SLC18A2(6571)

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Application

D-Amphetamine hemisulfate salt has been used in oxidative fermentative (OF) test, and exploratory test.

Actions biochimiques/physiologiques

D-Amphetamine is an active isomer of amphetamine. It induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites, which blocks catecholamine reuptake.

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Consulter la Bibliothèque de documents

Timothy J O'Neal et al.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 45(8), 1251-1262 (2019-11-21)
Opioid addiction has been declared a public health emergency, with fatal overdoses following relapse reaching epidemic proportions and disease-associated costs continuing to escalate. Relapse is often triggered by re-exposure to drug-associated cues, and though the neural substrates responsible for relapse
Cedric Jackson et al.
Behavioural brain research, 361, 131-138 (2018-12-15)
Although scientific research using mammalian models has made great strides in uncovering the enigmatic neural and molecular mechanisms orchestrating the state of drug addiction, a complete understanding has thus far eluded researchers. The complexity of the task has led to
A M Barr et al.
Pharmacology, biochemistry, and behavior, 64(3), 597-604 (1999-11-05)
The present study sought to determine the effect of withdrawal from an escalating dose schedule of d-amphetamine on sexual behavior in male rats. Tests were conducted every 5 days until stable levels of sexual behavior were obtained. With repeated testing
Stephanie A Carmack et al.
Neuroscience letters, 468(1), 18-22 (2009-10-27)
Much research is focused on developing novel drugs to improve memory. In particular, psychostimulants have been shown to enhance memory and have a long history of safe use in humans. In prior work, we have shown that very low doses
Yan Liu et al.
Proceedings of the National Academy of Sciences of the United States of America, 107(3), 1217-1222 (2010-01-19)
The prairie vole (Microtus ochrogaster) is a socially monogamous rodent species that forms pair bonds after mating, a behavior in which central dopamine (DA) has been implicated. Here, we used male prairie voles to examine the effects of drug exposure
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