Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf
51280
Hémine
BioXtra, from Porcine, ≥96.0% (HPLC)
Synonyme(s) :
Chloro(protoporphyrinato)fer(III), Chlorohémine, Chloroprotoporphyrine IX-fer(III), Chlorure de ferriprotoporphyrine IX, Hémine (chlorure)
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58,50 €
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About This Item
58,50 €
Produits recommandés
Source biologique
Porcine
Niveau de qualité
Gamme de produits
BioXtra
Essai
≥96.0% (HPLC)
Forme
powder or crystals
Technique(s)
tissue culture: suitable
transfection: suitable
Température de stockage
2-8°C
Chaîne SMILES
Cc1c(CCC(O)=O)c2cc3c(CCC(O)=O)c(C)c4cc5nc(cc6c(C)c(C=C)c(cc1n2)n6[Fe](Cl)n34)c(C=C)c5C
InChI
1S/C34H34N4O4.ClH.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);1H;/q;;+3/p-3/b25-13-,26-13-,27-14-,28-15-,29-14-,30-15-,31-16-,32-16-;;
Clé InChI
BTIJJDXEELBZFS-HXFTUNQESA-K
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Application
- Pour étudier des souches bactériennes et leurs conditions de croissance[1]
- Dans des essais à court terme sur des colonies (avec un milieu de culture constitué d′hémine et d′autres éléments)[2]
- Pour des transfections cellulaires[3]
Actions biochimiques/physiologiques
L′hémine peut servir à étudier l′expression et la répression de l′hème oxygénase 1 (HO-1) ainsi que l′activité de la HO-1. L′hématine est le « facteur X » nécessaire à la croissance d′Haemophilus influenzae.
Produit(s) apparenté(s)
Code de la classe de stockage
11 - Combustible Solids
Classe de danger pour l'eau (WGK)
WGK 3
Point d'éclair (°F)
Not applicable
Point d'éclair (°C)
Not applicable
Équipement de protection individuelle
Eyeshields, Gloves, type N95 (US)
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Les clients ont également consulté
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How is shipping temperature determined? And how is it related to the product storage temperature?
1 answer-
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How can I determine the shelf life / expiration / retest date of this product?
1 answer-
If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdfHelpful?
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What is the solubility of Hemin, product catalog # 51280, CAS 16009-13-5?
1 answer-
The product with code 51280 can be dissolved in DMSO at a concentration of 1 mM. It is also soluble in 1.4 M ammonium hydroxide at a concentration of 50 mg/ml, and this can be achieved by heating the solution at 95°C for 5 minutes, resulting in a dark brown solution. Additionally, a stock solution of 0.25% hemin in 50% triethanolamine can be prepared. CAS number 16009-13-5, which corresponds to product 51280, is soluble in 1.4 M NaOH at a concentration of 25 mg/mL, and it is practically insoluble in water.
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How can hemin be dissolved for cell culture experiments in macrophages? Is it necessary to couple it to serum/BSA?
1 answer-
This product has not been tested for use in cell culture. However, a previously deleted product, H1652, has been tested. The H1652 was dissolved at 10 mg/mL in 1 M NaOH and added then added to the culture medium at 7 mg/L. This information would need to be validated for product 51280.
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How stable are stock solutions of hemin (dissolved in 1N NaOH and diluted to 1 mM with dH2O)? Can they be stored at 4C or -20C?
1 answer-
The solution stability has not been determined.
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What is the Department of Transportation shipping information for this product?
1 answer-
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
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What is the solubility of Product 51280, Hemin?
1 answer-
Hemin can be dissolved in DMSO at 1 mM. This product should be soluble in 1.4 M ammonium hydroxide (50 mg/ml) with 5 minutes of heating at 95 °C, yielding a dark brown solution. A stock solution of 0.25% hemin in 50% triethanolamine can be made.
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