P2759

Phloxine B

Powder

• Synonyme(s) : 2′,4′,5′,7′-Tetrabromo-4,5,6,7-tetrachlorofluorescein disodium salt, Acid Red 92, Cyanosine, D&C;Red No. 28, Eosin 10B
• Formule empirique (notation de Hill): C₂₀H₂Br₄Cl₄Na₂O₅
• Numéro CAS: 18472-87-2
• Poids moléculaire : 829.63
• Numéro C.I. (Colour Index): 45410
• Numéro Beilstein : 3887100
• Numéro CE : 242-355-6
• Numéro MDL: MFCD00070627
• Code UNSPSC : 12171500
• ID de substance PubChem : 24898359
• Nomenclature NACRES : NA.47

Propriétés

• product name: Phloxine B, antibacterial fluorescent dye
• Niveau de qualité: 200
• Forme: powder
• Couleur: dark red
• Solubilité: water: 1 mg/mL, clear, red
• εmax: 1150-1300 at 546-550 nm in 50% ethanol
• Application(s): diagnostic assay manufacturing; hematology; histology
• Température de stockage: room temp
• Chaîne SMILES: [Na+].[Na+].[O-]c1c(Br)cc2c(Oc3c(Br)c([O-])c(Br)cc3C24OC(=O)c5c(Cl)c(Cl)c(Cl)c(Cl)c45)c1Br
• InChI: 1S/C20H4Br4Cl4O5.2Na/c21-5-1-3-17(9(23)15(5)29)32-18-4(2-6(22)16(30)10(18)24)20(3)8-7(19(31)33-20)11(25)13(27)14(28)12(8)26;;/h1-2,29-30H;;/q;2*+1/p-2
• Clé InChI: OOYIOIOOWUGAHD-UHFFFAOYSA-L

Description

Application

Phloxine B has been used to trace the uptake of double stranded RNA by green peach aphids. It has also been used to stain yeast strains.

Actions biochimiques/physiologiques

Phloxine B has been demonstrated as an alternative to Gram staining. It was found to inhibit the growth of methicillin-resistant Staphylococcus aureus. Phloxine B stimulated and inhibited the channel activity of wild-type cystic fibrosis transmembrane conductance regulator (CFTR). It has antibacterial properties. Phloxine B staining can be used to distinguish between gram-positive and gram-negative bacteria.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable
• Équipement de protection individuelle: Eyeshields, Gloves, type N95 (US)