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08012

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1-Deoxynojirimycin

analytical standard

Synonyme(s) :

1,5-Dideoxy-1,5-imino-D-sorbitol

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About This Item

Formule empirique (notation de Hill):
C6H13NO4
Numéro CAS:
Poids moléculaire :
163.17
Numéro Beilstein :
3588039
Numéro MDL:
Code UNSPSC :
85151701
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

analytical standard

Niveau de qualité

Pureté

≥95.0% (HPLC)

Durée de conservation

limited shelf life, expiry date on the label

Format

neat

Chaîne SMILES 

OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C6H13NO4/c8-2-3-5(10)6(11)4(9)1-7-3/h3-11H,1-2H2/t3-,4+,5-,6-/m1/s1

Clé InChI

LXBIFEVIBLOUGU-JGWLITMVSA-N

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Catégories apparentées

Description générale

1-Deoxynojirimycin is a polyhydroxypiperidine alkaloid and glucose analog, that has an -NH group substituting the O atom in the pyranose ring. It shows a significant α-glucosidase inhibitory effect in addition to antioxidant, antimicrobial, antidiabetic, antitumor, and anti-inflammatory behavior. It is commonly found in the roots of mulberry trees.

Application

DNJ may be used as a reference standard for the determination of DNJ in:
  • Mulberry leaves by high-performance liquid chromatography (HPLC) equipped with evaporative light scattering detector (ELSD) as well as direct analysis in real-time (DART) ionization source coupled with triple quadrupole tandem mass spectrometry (MS/MS).
  • Silkworms by hydrophilic interaction chromatography (HILIC) with MS/MS operating on multiple reaction monitoring (MRM) mode.
  • Mulberry leaves of 132 varieties belonging to nine Morus species following its derivatization with fluorenylmethyl chloroformate (FMOC-Cl) by high-performance liquid chromatography (HPLC) combined with photodiode array (PDA) detector
  • Development of an analytical method based on hydrophilic interaction chromatography (HILIC) coupled with tandem mass spectrometry (MS/MS) in positive ion electrospray ionization mode in the leaves of 32 cultivars of different Morus species
  • HPLC method-based separation and quantification in the ethanol extracts of the leaves of Morus alba L. and Morus nigra with fluorimetric detection following pre-column derivatization with 9-fluorenylmethyl chloroformate
  • 146 varieties of mulberry fruits from nine genera by HPLC in combination with UV-Vis dual-wavelength detection
  • Human plasma by hybrid quadrupole/linear ion trap tandem mass spectrometry (QTRAP MS/MS).

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable


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