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03685

Sigma-Aldrich

Acide éthylènediaminetétraacétique disodium salt dihydrate

≥97.0% (KT)

Synonyme(s) :

EDTA disodium salt, EDTA-Na2, Edétate disodium salt dihydrate, Sequestrene Na2, Édathamil, Éthylènediaminetétraacétate disodique dihydrate

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About This Item

Formule empirique (notation de Hill):
C10H14N2Na2O8 · 2H2O
Numéro CAS:
6381-92-6
Poids moléculaire :
372.24
Numéro Beilstein :
3900609
Numéro CE :
205-358-3
Code UNSPSC :
12352100
ID de substance PubChem :
24845550
Nomenclature NACRES :
NA.21

Niveau de qualité

300

Pureté

≥97.0% (KT)

Pf

248 °C (dec.) (lit.)

Solubilité

H2O: 100 g/L at 20 °C

Chaîne SMILES 

O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O

InChI

1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2

Clé InChI

OVBJJZOQPCKUOR-UHFFFAOYSA-L

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Catégories apparentées

Description générale

Ethylenediaminetetraacetic acid disodium salt dihydrate (EDTA-Na2), is a well known complexation agent with various uses in chemical synthesis, analytical chemistry, and biochemistry. In chemical synthesis, EDTA-Na2 combines with polyvalent cations to form a soluble non-ionic complex that can be removed from solution, which helps prevent undesired side reactions.

Application

Chélateur de cations divalents. Inhibe les enzymes dont l′activité exige des cations divalents, comme les métalloprotéinases.

Pictogrammes

Health hazardExclamation mark
GHS08,GHS07

Mention d'avertissement

Warning

Mentions de danger

H332,H373

Classification des risques

Acute Tox. 4 Inhalation - STOT RE 2 Inhalation

Organes cibles

Respiratory Tract

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Gloves, type N95 (US)

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Certificats d'analyse (COA)

Lot/Batch Number
BCCM0125
BCCM0650
BCCL5617
BCCL5618
BCCJ9328

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Suli Huang et al.
PloS one, 10(2), e0117007-e0117007 (2015-02-07)
microRNA (miRNA) plays a role in the pathogenesis of ischemic stroke, and single nucleotide polymorphisms in miRNA genes may contribute to disease susceptibility. However, the effect of miR-146a, miR-196a2, and miR-499 polymorphisms on ischemic stroke susceptibility has been rarely reported.
Lisa M Ryno et al.
Biomacromolecules, 15(8), 2944-2951 (2014-07-18)
End-functionalized macromolecular starch reagents, prepared by reductive amination, were grafted onto a urethane-linked polyester-based backbone using copper-catalyzed azide-alkyne cycloaddition (CuAAC) chemistry to produce novel amphiphilic hybrid graft copolymers. These copolymers represent the first examples of materials where the pendant chains
Sabrina Lusvarghi et al.
Nucleic acids research, 41(13), 6637-6649 (2013-05-04)
Interaction between the viral protein Rev and the RNA motifs known as Rev response elements (RREs) is required for transport of unspliced and partially spliced human immunodeficiency virus (HIV)-1 and HIV-2 RNAs from the nucleus to the cytoplasm during the
Haiyan Zhang et al.
Analytica chimica acta, 770, 140-146 (2013-03-19)
A novel method for selective determination of Cr(III) and Cr(VI) in environmental water samples was developed based on target-induced fluorescence quenching of glutathione-stabilized gold nanoclusters (GSH-Au NCs). Fluorescent GSH-Au NCs were synthesized by a one-step approach employing GSH as reducing/protecting
Gervasio A Lamas et al.
JAMA, 309(12), 1241-1250 (2013-03-28)
Chelation therapy with disodium EDTA has been used for more than 50 years to treat atherosclerosis without proof of efficacy. To determine if an EDTA-based chelation regimen reduces cardiovascular events. Double-blind, placebo-controlled, 2 × 2 factorial randomized trial enrolling 1708
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