GF302

BMP-4 Protein, Human Recombinant Animal Free

Bone morphogenetic protein 4 (BMP4) is a TGFβ superfamily lig& that is widely expressed from early embryogenesis through adulthood. The Recombinant animal free human BMP-4 protein is manufactured using all non-animal reagents.

• Synonyme(s) : BMP4, Bone morphogentic protein-4, DVR-4
• Code UNSPSC : 12352202
• eCl@ss : 32160405
• Nomenclature NACRES : NA.77

Propriétés

• Produit recombinant: expressed in E. coli
• Niveau de qualité: 100
• Essai: >98% (SDS-PAGE and HPLC)
• Impuretés: <0.1 μg/mg protein endotoxin (<1EU/μg)
• Numéro d'accès NCBI: NM_001202.3; NM_130850.2; NM_130851.2
• Numéro d'accès UniProt: P12644
• Conditions d'expédition: dry ice

Description

Description générale

Bone morphogentic protein 4 (BMP4) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood. It plays an important role in mesenchyme formation, epidermal determination, suppression of neural induction, the development of multiple organs, and tissue repair. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva.
Animal free human recombinant BMP4 is a fully active homodimeric protein consisting of two 107 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.

Product Source: E. coli

Spécificité

Cross Reactivty
Mouse

Application

Research Category
Stem Cell Research

Research Sub Category
Growth Factors & Receptors

Qualité

Bioactivity assay: Determined by its ability to induce alkaline phosphatase production by ATDC-5 cells. The expected ED50 for this effect is 5-10 ng/ml.

Forme physique

Product is filtered through a 0.2 micron filter before lyophilization.

Recombinant animal free human BMP-4 is manufactured using all non-animal reagents

Stockage et stabilité

Store at -20°C for up to 6 months from date of receipt.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable