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EZML

Millipore

Mouse Leptin ELISA Kit

measures and quantifies Leptin levels in 10 μL serum or plasma

Synonyme(s) :

Leptin, Obesity factor

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About This Item

Code UNSPSC :
12161503
eCl@ss :
32161000
Nomenclature NACRES :
NA.32

product name

Mouse Leptin ELISA, This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.

Niveau de qualité

200

Espèces réactives

mouse

Conditionnement

kit of 1 × 96 wells

Paramètres

10 μL sample volume (4hr assay)

assay range

accuracy: 87-100%
linearity: 100-111%
sensitivity: 0.05 ng/mL
standard curve range: 0.2-30 ng/mL

Technique(s)

ELISA: suitable

Entrée

sample type serum
sample type plasma (K2 EDTA)

Numéro d'accès UniProt

P41159
P41160

Application(s)

research use

Méthode de détection

colorimetric (450nm/590nm)

Conditions d'expédition

wet ice

Température de stockage

2-8°C

Catégories apparentées

Description générale

Mouse Leptin ELISA is used to measure and quantify leptin levels in metabolism, endocrine, and neuroscience research. Leptin is a hormone or cytokine derived from adipocytes circulating in the blood. It acts as a regulator of food intake and energy expenditure via the hypothalamus. This hormone plays a role in angiogenesis, lipid and carbohydrate metabolism, and hematopoiesis. Leptin exerts its effects on the cardiovascular, reproductive, and immune systems. The deficiency of leptin in rodents is associated with obesity and insulin resistance.

Application

Mouse Leptin ELISA has been used to determine the levels of leptin in mice serum and plasma.

Clause de non-responsabilité

For research use only. Not for use in diagnostic procedures.

Pictogrammes

CorrosionExclamation mark
GHS05,GHS07

Mention d'avertissement

Warning

Mentions de danger

H290,H317

Classification des risques

Met. Corr. 1 - Skin Sens. 1

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Certificats d'analyse (COA)

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Consulter la Bibliothèque de documents

Tamiris Lima Rachid et al.
Molecular and cellular endocrinology, 402, 86-94 (2015-01-13)
Browning is characterized by the formation of beige/brite fat depots in subcutaneous white adipose tissue (sWAT). This study aimed to examine whether the chronic activation of PPARalpha by fenofibrate could induce beige cell depots in the sWAT of diet-induced obese
Lin Xu et al.
The Journal of clinical investigation, 118(1), 272-280 (2007-12-22)
Leptin is a hormone that reduces excitability in some hypothalamic neurons via leptin receptor activation of the JAK2 and PI3K intracellular signaling pathways. We hypothesized that leptin receptor activation in other neuronal subtypes would have anticonvulsant activity and that intranasal
Night eating and obesity in the EP3R-deficient mouse.
Manuel Sanchez-Alavez, Izabella Klein, Sara E Brownell, Iustin V Tabarean et al.
Proceedings of the National Academy of Sciences of the USA null
Timothy M Griffin et al.
Arthritis and rheumatism, 60(10), 2935-2944 (2009-10-01)
To test the hypothesis that obesity resulting from deletion of the leptin gene or the leptin receptor gene results in increased knee osteoarthritis (OA), systemic inflammation, and altered subchondral bone morphology. Leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) female mice compared
Prostate cancer cell proliferation and angiogenesis in different obese mice models.
Ribeiro AM, Andrade S, Pinho F, Monteiro JD, Costa M, Lopes C, Aguas AP, Monteiro MP
International Journal of Experimental Pathology null
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