8.20112

Anthranilic acid

for synthesis

• Synonyme(s) : Anthranilic acid, 2-Aminobenzoic acid
• Formule linéaire : 2-(NH₂)C₆H₄COOH
• Numéro CAS: 118-92-3
• Poids moléculaire : 137.14
• Numéro MDL: MFCD00007712
• Code UNSPSC : 12352106
• Numéro de classement CE : 204-287-5
• Nomenclature NACRES : NA.22

Propriétés

• Pression de vapeur: 0.001 hPa ( 52.6 °C)
• Niveau de qualité: 200
• Pureté: ≥99.0% (acidimetric)
• Forme: solid
• Température d'inflammation spontanée: >530 °C
• Puissance: 4550 mg/kg LD₅₀, oral (Rat)
• Pf: 146-148 °C
• Température de transition: flash point 150 °C
• Solubilité: 4.5 g/L
• Densité: 1.383 g/cm³ at 23 °C
• Masse volumique apparente: 500 kg/m³
• Température de stockage: 2-30°C
• InChI: 1S/C7H7NO2/c8-6-4-2-1-3-5(6)7(9)10/h1-4H,8H2,(H,9,10)
• Clé InChI: RWZYAGGXGHYGMB-UHFFFAOYSA-N

Description

Application

• Anthranilic acid in bio-imaging: Anthranilic acid produced by Virgibacillus salarius MML1918 was characterized for its potential in bio-imaging applications, demonstrating utility in visualizing biological processes (Nandhagopal and Narayanasamy, 2024).


• Anthranilic acid as a metabolite biomarker: A study utilized targeted metabolomics to identify anthranilic acid as a biomarker in Salmonella enteritidis-contaminated chickens, enhancing detection and safety measures in food chemistry (Chen et al., 2023).


• Anthranilic acid in metabolic pathway analysis: A comparative study on the kynurenine pathway in cell lines incorporated anthranilic acid, utilizing LC-MS/MS-based targeted metabolomics to explore selective inhibition of indoleamine and tryptophan 2,3-dioxygenases (Villani et al., 2024).


• Anthranilic acid in quantitative metabolomics: Liquid chromatography-tandem mass spectrometry was used for the simultaneous quantification of tryptophan, serotonin, and kynurenine pathway metabolites, including anthranilic acid, in various biological samples, aiding in comprehensive metabolic profiling (Frobel et al., 2023).

Remarque sur l'analyse

Assay (acidimetric): ≥ 99.0 %
Melting range (lower value): ≥ 144 °C
Melting range (upper value): ≤ 147 °C
Identity (IR): passes test

Informations sur la sécurité

• Pictogrammes: GHS05
• Mention d'avertissement: Danger
• Mentions de danger: H318
• Conseils de prudence: P280 - P305 + P351 + P338
• Classification des risques: Eye Dam. 1
• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): 302.0 °F - closed cup
• Point d'éclair (°C): 150 °C - closed cup