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6-Acetylmorphine, 1.0 mg/mL solution

1 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonyme(s) :

6-Acetylmorphine solution

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About This Item

Formule empirique (notation de Hill):
C19H21NO4
Numéro CAS:
Poids moléculaire :
327.37
Numéro MDL:
Code UNSPSC :
41116107
ID de substance PubChem :
Nomenclature NACRES :
NA.24

Qualité

certified reference material

Forme

liquid

Caractéristiques

SNAP-N-SPIKE®. SNAP-N-SHOOT®

Conditionnement

ampule of 1 mL

Fabricant/nom de marque

Cerilliant®

drug control

Narcotic Licence Schedule A (Switzerland); estupefaciente (Spain); Decreto Lei 15/93: Tabela IA (Portugal)

Concentration

1 mg/mL in acetonitrile

Technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

Application(s)

forensics and toxicology

Format

single component solution

Température de stockage

2-8°C

Chaîne SMILES 

CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35

InChI

1S/C19H21NO4/c1-10(21)23-15-6-4-12-13-9-11-3-5-14(22)17-16(11)19(12,18(15)24-17)7-8-20(13)2/h3-6,12-13,15,18,22H,7-9H2,1-2H3/t12-,13+,15-,18-,19-/m0/s1

Clé InChI

JJGYGPZNTOPXGV-SSTWWWIQSA-N

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Catégories apparentées

Description générale

6-Acetylmorphine, also known as 6-monoacetylmorphine or 6-MAM, is an active metabolite of heroin and biomarker for heroin usage. This Certified Spiking Solution® is suitable for use as a starting material in calibrators and controls for GC/MS or LC/MS methods in forensic analysis, clinical toxicology, urine drug testing, or pain prescription monitoring. It is relatively difficult to detect in urine samples as it has a short detection window. Within minutes after heroin administration (intravenously), 6-acetylmorphine appears in the saliva and is found at a higher concentration than in plasma.

Application


  • Forensic toxicology reference: 6-Acetylmorphine is used as a key analytical reference material in forensic toxicology to identify heroin use in morphine-positive urine specimens, aiding in the differentiation between pharmaceutical and illicit opioid consumption (Vikingsson et al., 2024).

  • Opiate research chemical: This compound serves as a high-purity standard for opioid research, facilitating the study of opioid metabolism and the development of new analytical techniques in bioanalytical studies (Liu et al., 2024).

Informations légales

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTIONS is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Produit(s) apparenté(s)

Réf. du produit
Description
Tarif

Pictogrammes

FlameExclamation mark

Mention d'avertissement

Danger

Classification des risques

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Code de la classe de stockage

3 - Flammable liquids

Classe de danger pour l'eau (WGK)

WGK 2

Point d'éclair (°F)

42.8 °F - closed cup

Point d'éclair (°C)

6.0 °C - closed cup


Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

High prevalence of 6-acetylmorphine in morphine-positive oral fluid specimens.
Presley
Forensic Science International, 133(1-2) (2003)
Joseph Jones
Journal of Analytical Toxicology, 171-175 (2002)
Forensic drug testing for opiates: I. Detection of 6-acetylmorphine in urine as an indicator of recent heroin exposure; drug and assay considerations and detection times.
Cone EJ
Journal of Analytical Toxicology (1991)
Forensic Science International null
Cai Tie et al.
Journal of mass spectrometry : JMS, 47(11), 1429-1434 (2012-11-14)
With the combination of high separation ability of capillary electrophoresis (CE) and strong identification ability of mass spectrometry (MS), CE/MS is becoming a powerful tool for polar and ionic analytes analysis. Different interfaces have been developed to enhance the sensitivity

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