807788

palmitic-acid-9-hydroxy-stearic-acid

95%

• Synonyme(s) : 9-PAHSA
• Formule empirique (notation de Hill): C₃₄H₆₆O₄
• Poids moléculaire : 538.89
• Code UNSPSC : 12352106
• ID de substance PubChem : 329768748
• Nomenclature NACRES : NA.22

Propriétés

• Niveau de qualité: 100
• Pureté: 95%
• Forme: solid
• Pf: 33.5 °C
• Température de stockage: 2-8°C
• Chaîne SMILES: CCCCCCCCCC(OC(CCCCCCCCCCCCCCC)=O)CCCCCCCC(O)=O
• InChI: 1S/C34H66O4/c1-3-5-7-9-11-12-13-14-15-16-18-23-27-31-34(37)38-32(28-24-20-17-10-8-6-4-2)29-25-21-19-22-26-30-33(35)36/h32H,3-31H2,1-2H3,(H,35,36)
• Clé InChI: MHQWHZLXDBVXML-UHFFFAOYSA-N

Description

Description générale

Palmitic-acid-9-hydroxy-stearic-acid (9-PAHSA) is an isomeric form of bioactive fatty acid ester of hydroxyl-fatty acid (FAHFA).

Application

9-PAHSA is composed of palmitic acid attached to stearic acid and is in the class of branched lipids referred to as fatty acid esters of hydroxy fatty acids (FAHFAs). 9-PAHSA was found at increased levels in serum and white adipose tissue of insulin-sensitive mice. Levels were found to be lower in white adipose tissue of insulin-resistant humans. Studies of oral administration of 9-PAHSA to obese, diabetic mice showed improved glucose tolerance. In characterizing the mechanism, it was found that 9-PAHSA stimulates insulin and GLP-1 secretion and also enhances glucose transport and the Glut4 transporter through activation of GPR-120. 9-PAHSA was also shown to have anti-inflammatory properties.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable