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779873

Sigma-Aldrich

Méthyl-β-cyclodextrine

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science, ≥98.0% cyclodextrin basis

Synonyme(s) :

Cavasol® W7 M Life Science, MβCD, Methyl-beta-cyclodextrin

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About This Item

Numéro CAS:
128446-36-6
Code UNSPSC :
12352201
Nomenclature NACRES :
NA.22

Qualité

Produced by Wacker Chemie AG, Burghausen, Germany, Life Science

Pureté

≥98.0% cyclodextrin basis

Forme

powder

Activité optique

[α]/D 154.0 to 156.0°

Poids mol.

Mw 1310 g/mol

Ampleur du marquage

1.7-1.9 molar substitution

Impuretés

≤0.10% unsubstituted cyclodextrin
≤0.20% chloride
≤0.50% reducing substances
≤50 ppm volatile organics

Résidus de calcination

≤0.50%

Perte

≤5.0% loss on drying

Couleur

white to off-white

Pf

180-182 °C (lit.)

Absorption

≤0.10 at 350-600 nm in solution at 10%
≤1.00 at 220-350 nm in solution at 10%

InChI

1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3

Clé InChI

QGKBSGBYSPTPKJ-UHFFFAOYSA-N

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Catégories apparentées

Application

Methyl-β-cyclodextrin is a macrocyclic compound that can form inclusion complexes with a number of guest molecules. It shows higher solubility in aqueous solutions and greater solubilizing and complexing power compared to the parent β-cyclodextrin. MβCD can be used to enhance the enzyme activity and enantioselectivity of subtilisin enzyme in organic solvents.

Autres remarques

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
For R&D Use

Informations légales

Cavasol is a registered trademark of Wacker Chemie AG

Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

368.6 °F

Point d'éclair (°C)

187 °C

Certificats d'analyse (COA)

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Improved enzyme activity and enantioselectivity in organic solvents by methyl-?-cyclodextrin.
Griebenow K
Journal of the American Chemical Society, 121(36), 8157-8163 (1999)
Preparation and solid-state characterization of inclusion complexes formed between miconazole and methyl-?-cyclodextrin.
Ribeiro A
Aaps Pharmscitech, 9(4), 1102-1109 (2008)
Sara Rodríguez-Acebes et al.
The Biochemical journal, 420(2), 305-315 (2009-03-06)
Cholesterol homoeostasis is critical for cell viability and proliferation. The SREBP (sterol regulatory element-binding protein) pathway is crucial for the maintenance of cholesterol homoeostasis. This pathway is controlled by cholesterol and cholesterol-derived oxysterols. J774 cells cannot convert desmosterol into cholesterol
Mario Menschikowski et al.
Cancer cell international, 11, 4-4 (2011-02-16)
Increasing evidences show that beyond its role in coagulation, endothelial protein C receptor (EPCR) interferes with carcinogenesis. Pro-carcinogenic effects of EPCR were linked with a raised generation of activated protein C (aPC) and anti-apoptotic signalling. This study was carried out
Laurie Hamtiaux et al.
PloS one, 6(10), e26823-e26823 (2011-11-03)
The antitumoral properties of endocannabinoids received a particular attention these last few years. Indeed, these endogenous molecules have been reported to exert cytostatic, apoptotic and antiangiogenic effects in different tumor cell lines and tumor xenografts. Therefore, we investigated the cytotoxicity
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