GRIN2A
glutamate receptor, ionotropic, N-methyl D-aspartate 2A
Synonymes:
EPND, GluN2A, NMDAR2A, NR2A
Espèce(s):
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
ID UniProtKB:
ID du gène:
- Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
- Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
- Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
- domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
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Small Molecule - Agonist
Référence du produit
Description
Espèce(s)
Dextromethorphan HBr, certified reference material, pharmaceutical secondary standard,
Espèce(s)
human
Dextromethorphan hydrobromide, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Small Molecule - Allosteric Modulator
Référence du produit
Description
Espèce(s)
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Espèce(s)
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Small Molecule - Antagonist
Référence du produit
Description
Espèce(s)
Glycine, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
Espèce(s)
rat
Antibodies
Référence du produit
Description
Espèces réactives
Application
Anti-NR2A Antibody, clone A12W, rabbit monoclonal, culture supernatant, clone A12W, Upstate®,
Espèces réactives
mouse, rat
Application
western blot
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Espèces réactives
fish, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-NR2A Antibody, Upstate®, from rabbit,
Espèces réactives
mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
Espèces réactives
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-phospho NMDAR2A (Ser1459), ,
Espèces réactives
human
Application
immunocytochemistry
western blot
western blot
Small Molecule - Blocker
Référence du produit
Description
Espèce(s)
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Espèce(s)
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Small Molecule - Inhibitor
Référence du produit
Description
Espèce(s)
Small Molecule - Mixed Agonist/Antagonist
Référence du produit
Description
Espèce(s)