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Merck

ADRB2

adrenoceptor beta 2, surface

Synonymes:
ADRB2R, ADRBR, B2AR, BAR, BETA2AR
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(154) Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008]
  • Mouse(11555) adrenergic receptor, beta 2
  • Rat(24176) adrenoceptor beta 2, surface
  • cow(281605) adrenergic, beta-2-, receptor, surface
  • Horse(100060659) adrenoceptor beta 2, surface
  • domestic cat(493767) adrenoceptor beta 2, surface
  • naked mole-rat(101708921) adrenoceptor beta 2, surface
  • domestic guinea pig(100722663) adrenoceptor beta 2, surface
  • dog(403910) adrenoceptor beta 2, surface
  • chicken(427623) adrenergic, beta-2-, receptor, surface
  • Domestic Rabbit(100340821) adrenoceptor beta 2, surface
  • sheep(100170320) adrenoceptor beta 2, surface

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numéro du produit
Description
Espèce(s)
(−)-Isoproterenol hydrochloride, ,
Espèce(s)
human
Clenbuterol hydrochloride, ≥95%,
Espèce(s)
human
Salbutamol, ,
Espèce(s)
human
Formoterol fumarate dihydrate, >98% (HPLC),
Espèce(s)
human
Albuterol sulfate, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human

Small Molecule - Antagonist

Numéro du produit
Description
Espèce(s)
ICI 118,551 hydrochloride, ≥98% (HPLC), powder,
Espèce(s)
human
Propranolol hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Espèce(s)
human
Propranolol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Nadolol, analytical standard,
Espèce(s)
human
Timolol maleate, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

Antibodies

Numéro du produit
Description
Espèces réactives
Application
Anti-ADRB2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunofluorescence

western blot
Anti-β2-Adrenergic Receptor Antibody, clone 2B23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Espèces réactives
human
Application
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ADRB2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunohistochemistry
Anti-Adrenergic Receptor β2 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-Adrenergic Receptor B2 (pSer355+Ser356) antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human, mouse, rat
Application
ELISA
immunohistochemistry

western blot

Small Molecule - Blocker

Numéro du produit
Description
Espèce(s)
Sotalol hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human
Sotalol hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Espèce(s)
human
(±)-Sotalol hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
(S)-(−)-Propranolol hydrochloride, ≥98% (TLC), powder,
Espèce(s)
human
Propafenone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Espèce(s)
human

esiRNA

Numéro du produit
Description
Espèce(s)
MISSION® esiRNA, targeting human ADRB2,
Espèce(s)
human
MISSION® esiRNA, targeting mouse Adrb2,
Espèce(s)
mouse