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D4025

Dimetridazole

Synonym(s):

1,2-Dimethyl-5-nitroimidazole

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About This Item

Empirical Formula (Hill Notation):
C5H7N3O2
CAS Number:
Molecular Weight:
141.13
UNSPSC Code:
51102829
NACRES:
NA.85
PubChem Substance ID:
EC Number:
209-001-2
Beilstein/REAXYS Number:
130665
MDL number:


form

powder

color

almost white to brownish-yellow

solubility

ethanol: sparingly soluble 96%, H2O: slightly soluble, chloroform: freely soluble, ether: slightly soluble

antibiotic activity spectrum

Gram-negative bacteria, parasites

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

SMILES string

Cc1ncc(n1C)[N+]([O-])=O

InChI

1S/C5H7N3O2/c1-4-6-3-5(7(4)2)8(9)10/h3H,1-2H3

InChI key

IBXPYPUJPLLOIN-UHFFFAOYSA-N

Application

It is a potential antimicrobial agent against Campylobacter spp. from pigs[1]. It has been used to study antitrichomonad action on Tritrichomonas foetus[2]. Dimetridazole is used to study mechanisms of anti-protozoan nitroimidazole drugs.


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Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves



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M Sánchez-Polo et al.
Water research, 43(16), 4028-4036 (2009-06-23)
The main objectives of this study were: (1) to investigate the decomposition and mineralization of nitroimidazoles (Metronidazole [MNZ], Dimetridazole [DMZ], and Tinidazole [TNZ]) in waste and drinking water using gamma irradiation; (2) to study the decomposition kinetics of these nitroimidazoles;
M-P Callait-Cardinal et al.
The Veterinary record, 161(17), 581-585 (2007-10-30)
Between April 2003 and March 2005, 113 outbreaks of histomonosis were recorded in standard turkey farms in France, and 15 cases were recorded in turkey breeding centres. Most of the cases were in north-west France, the principal farming area for
M G Müller et al.
Veterinary parasitology, 152(1-2), 67-78 (2008-01-02)
Four falcons from a private collection of 137 falcons in Abu Dhabi (UAE) died suddenly in summer 2005. In order to screen for a possible disease among the remaining falcons in the aviary, all other birds were caught, examined and



Global Trade Item Number

SKUGTIN
D4025-100G04061833563922
D4025-1KG04061826718315

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