D1444
6,2′-Dihydroxyflavone
≥98% (HPLC), powder
Synonym(s):
6-hydroxy-2-(2-hydroxyphenyl)-4H-1-benzopyran-4-one, DHF
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About This Item
Empirical Formula (Hill Notation):
C15H10O4
Molecular Weight:
254.24
NACRES:
NA.77
UNSPSC Code:
12352200
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white
solubility
DMSO: >10 mg/mL
storage temp.
room temp
Biochem/physiol Actions
6,2′-Dihydroxyflavone is a partial inverse agonist at GABAA receptors with α-subunit selectivity.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Eye Dam. 1
Storage Class
6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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Articles
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Feng Wang et al.
Neuropharmacology, 53(4), 574-582 (2007-08-08)
Neuroactivity of a number of flavonoids is mediated by modulation of type A gamma-aminobutyric acid (GABA(A)) receptor function via benzodiazepine sites, mostly as partial agonists. In the present study, 6,2'-dihydroxyflavone (DHF) was characterized for potential inverse agonistic activity, and its
Global Trade Item Number
| SKU | GTIN |
|---|---|
| D1444-25MG | 04061832260211 |
| D1444-5MG | 04061832071886 |