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PC730

Anti-IDE, N-Terminal (97-273) Rabbit pAb

liquid, Calbiochem®

Synonym(s):

Anti-Insulin Degrading Enzyme, Anti-BC2

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About This Item

NACRES:
NA.41
UNSPSC Code:
12352203
Clone:
polyclonal
Species reactivity:
rat, human, hamster, mouse
Application:
Citations:
22


biological source

rabbit

Quality Level

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

form

liquid

contains

≤0.1% sodium azide as preservative

species reactivity

rat, human, hamster, mouse

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze, avoid repeated freeze/thaw cycles

dilution

(ELISA (direct only) (1:2000-1:4000)
Immunoblotting (1:500-1:4000)
Immunocytochemistry (1:200-1:1000)
Immunoprecipitation (not recommended))

isotype

IgG

shipped in

wet ice

storage temp.

−70°C

target post-translational modification

unmodified

Gene Information

human ... IDE(3416)

General description

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~115 kDa endogenous as well as recombinant IDE protein.
Recognizes the ~115 kDa endogenous and recombinant IDE.
This Anti-IDE, N-Terminal (97-273) Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunocytochemistry, Immunoprecipitation for the detection of IDE, N-Terminal (97-273).

Immunogen

Rat
a recombinant protein consisting of amino acids 97-273 of rat IDE fused to GST

Application

ELISA (direct only) (1:2000-1:4000)

Immunoblotting (1:500-1:4000)

Immunocytochemistry (1:200-1:1000)

Immunoprecipitation (not recommended)

Physical form

Undiluted serum.

Preparation Note

Following initial thaw, aliquot and freeze (-70°C).

Analysis Note

Positive Control
Rat or mouse liver cytosol

Other Notes

Antibody should be titrated for optimal results in individual systems.
Morelli, L., et al. 2003. J. Biol. Chem.278, 23221.
Kurochkin, I.V. and Goto, S. 1994. FEBS Lett.345, 33.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

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Quality Level

100

Quality Level

200

Quality Level

100

Quality Level

100

antibody form

serum

antibody form

purified antibody

antibody form

serum

antibody form

affinity isolated antibody

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

rat, human, hamster, mouse

species reactivity

rat, mouse, human

species reactivity

Drosophila, hamster, rat, human, monkey, mouse

species reactivity

bovine, human, mouse, sheep, rat

Gene Information

human ... IDE(3416)

Gene Information

human ... IDE(3416)

Gene Information

-

Gene Information

human ... PTGS2(5743)

shipped in

wet ice

shipped in

ambient

shipped in

wet ice

shipped in

wet ice


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Storage Class

10 - Combustible liquids

wgk

WGK 1



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Journal of immunology (Baltimore, Md. : 1950), 186(12), 6925-6932 (2011-05-10)
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The American journal of pathology, 179(3), 1095-1103 (2011-07-19)
The accumulation of β-amyloid protein (Aβ) in the brain is thought to be a primary etiologic event in Alzheimer's disease (AD). Fibrillar Aβ plaques, a hallmark of AD abnormality, are closely associated with activated microglia. Activated microglia have contradictory roles



Global Trade Item Number

SKUGTIN
PC730-100UL04055977207910

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