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369334

2-Guanidinoethylmercaptosuccinic Acid

≥99% (TLC), carboxypeptidase B-like processing enzyme inhibitor, solid

Synonym(s):

2-Guanidinoethylmercaptosuccinic Acid, GEMSA

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About This Item

CAS Number:
77482-44-1
MDL number:
MFCD00036862
UNSPSC Code:
12352106
NACRES:
NA.77

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Product Name

2-Guanidinoethylmercaptosuccinic Acid, Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM).

SMILES string

S(C(CC(=O)O)C(=O)O)CCN=C(N)N

InChI

1S/C7H13N3O4S/c8-7(9)10-1-2-15-4(6(13)14)3-5(11)12/h4H,1-3H2,(H,11,12)(H,13,14)(H4,8,9,10)

InChI key

VKVCLXDFOQQABP-UHFFFAOYSA-N

assay

≥99% (TLC)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

solubility

water: soluble

shipped in

ambient

storage temp.

2-8°C

Quality Level

100

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This Item
444225361555444244
2-Guanidinoethylmercaptosuccinic Acid Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM).

Sigma-Aldrich

369334

2-Guanidinoethylmercaptosuccinic Acid

MMP-3 Inhibitor II The MMP-3 Inhibitor II, also referenced under CAS 161314-17-6, controls the biological activity of MMP-3. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444225

MMP-3 Inhibitor II

GSK-3 Inhibitor XIII The GSK-3 Inhibitor XIII, also referenced under CAS 404828-08-6, controls the biological activity of GSK-3. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Sigma-Aldrich

361555

GSK-3 Inhibitor XIII

MMP-2 Inhibitor I The MMP-2 Inhibitor I, also referenced under CAS 10335-69-0, controls the biological activity of MMP-2. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.

Sigma-Aldrich

444244

MMP-2 Inhibitor I

form

solid

form

solid

form

solid

form

solid

assay

≥99% (TLC)

assay

≥98% (TLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

manufacturer/tradename

Calbiochem®

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

storage temp.

2-8°C

storage temp.

10-30°C

storage temp.

2-8°C

storage temp.

−20°C

solubility

water: soluble

solubility

DMSO: 30 mg/mL, ethanol: 8 mg/mL

solubility

DMSO: 5 mg/mL

solubility

DMSO: 2 mg/mL, ethanol: 3 mg/mL

Biochem/physiol Actions

Cell permeable: no
Primary Target
Enkephalin convertase
Product does not compete with ATP.
Reversible: no
Target Ki: 8.8 nM for enkephalin convertase

Disclaimer

Toxicity: Standard Handling (A)

General description

Potent inhibitor of a carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.
Potent inhibitor of carboxypeptidase B-like processing enzyme referred to as enkephalin convertase (Ki = 8.8 nM). Ideal for use in affinity chromatography of the enzyme.

Other Notes

Bommer, M., et al. 1989. Brain Res. 492, 305.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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