Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

1.41544

SAFC

Parteck® MXP (Polyvinyl alcohol 3-82)

EMPROVE® ESSENTIAL, Ph. Eur.

Pharma Manufacturing

Synonym(s):

Parteck® Polyvinyl alcohol, PVA, Polyvinyl alcohol

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Linear Formula:
(C2H4O)n
CAS Number:
9002-89-5
MDL number:
MFCD00081922
UNSPSC Code:
12352104
Pricing and availability is not currently available.

Agency

Ph. Eur.

Quality Level

500

product line

EMPROVE® ESSENTIAL

form

powder

application(s)

pharmaceutical
solid formulation
solubility enhancement

storage temp.

15-25°C

InChI

1S/C2H4O/c1-2-3/h2-3H,1H2

InChI key

IMROMDMJAWUWLK-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Related Categories

General description

With a lower degree of hydrolysis along the PVA chain, Parteck® MXP 3-82 Polyvinyl alcohol is especially beneficial in forming strong interac­tions with hydrophobic drug molecules – in the solid state and in solution. Due to this, Parteck® MXP 3-82 excipient has very high capabilities as a precipitation inhibitor and can maintain high levels of supersaturation for physiologi­cally relevant timescales. As a result, Parteck® MXP 3-82 Polyvinyl alcohol can provide solubility enhancement for even the most challenging molecules.

Application

Parteck® MXP 3-82 is a PVA-based excipient that is used in Hot Melt Extrusion for Solubility Enhancement in oral solid dosage forms.

Features and Benefits

  • Superior supersaturation performance via precipitation inhibition
  • High thermostability up to 250°C, extending the potential application range
  • Stable high drug loads and suitability with a broad range of APIs
  • Flexible release kinetics
  • Compatible with several downstream processing capabilities, like direct compression, continuous manufacturing, thin film extrusion and 3D printing
  • Optimized powder properties for excellent performance in the HME process
  • Suitable polymer properties for HME, spray drying and 3D printing processes

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
PARTECK is a registered trademark of Merck KGaA, Darmstadt, Germany

Application

Product No.
Description
Pricing

also commonly purchased with this product

Product No.
Description
Pricing

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

No data available

Flash Point(C)

No data available

What is the Emprove® Program?

The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

Material Qualification Dossier

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Quality Management Dossier (Open Access)

Free of charge - Sign in to download

Operational Excellence Dossier

Available by subscription or for a fee

Operational Excellence Dossier

Available by subscription or for a fee

Learn more about the benefits an Emprove® Program subscription can provide
Why are these documents unavailable?
Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Articles

Solid Formulation Development Using Melt-based 3D Printing Technologies

3D printing can overcome challenges during formulation development, with a focus on enhancing API bioavailability in solid dispersions. Find out how in this technical article.

API Solubility and Dissolution Enhancement Via Formulation

Our overview of API solubility and dissolution enhancement methods can help you decide between the many options to take during formulation.

Related Content

3D Printed Precision: Selective Laser Sintering for Oral Drug Delivery

For selective laser sintering (SLS) polymers are needed for a successful workflow and selection of the best approach requires consideration of several factors.

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service