Direkt zum Inhalt
Merck

Very bright europium complexes that stain cellular mitochondria.

Chemical communications (Cambridge, England) (2013-01-22)
James W Walton, Adrien Bourdolle, Stephen J Butler, Marine Soulie, Martina Delbianco, Brian K McMahon, Robert Pal, Horst Puschmann, Jurriaan M Zwier, Laurent Lamarque, Olivier Maury, Chantal Andraud, David Parker
ZUSAMMENFASSUNG

The synthesis, structure and photophysical properties of a series of highly emissive europium complexes is reported. Certain complexes enter mammalian cells by macropinocytosis and stain the mitochondria selectively, allowing observation of the Eu emission in cellulo by time-gated spectral imaging.

MATERIALIEN
Produktnummer
Marke
Produktbeschreibung

Sigma-Aldrich
Amiloride hydrochloride hydrate, ≥98% (HPLC), powder
Sigma-Aldrich
Wortmannin aus Penicillium funiculosum, from Penicillium funiculosum, ≥98% (HPLC and TLC)
Sigma-Aldrich
Wortmannin, Ready Made Solution, from Penicillium funiculosum, ≥95% (HPLC)