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Merck

CRM03054

Supelco

Tetramethrin

mixture of stereoisomers, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

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About This Item

Empirische Formel (Hill-System):
C19H25NO4
CAS-Nummer:
Molekulargewicht:
331.41
Beilstein:
8807938
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

certified reference material
TraceCERT®

Qualitätsniveau

Produktlinie

TraceCERT®

Haltbarkeit

limited shelf life, expiry date on the label

Zusammensetzung

cis-Tetramethrin, <25.0% (minor component)

Hersteller/Markenname

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Lagertemp.

−20°C

SMILES String

C\C(C)=C\C1C(C(=O)OCN2C(=O)C3=C(CCCC3)C2=O)C1(C)C

InChI

1S/C19H25NO4/c1-11(2)9-14-15(19(14,3)4)18(23)24-10-20-16(21)12-7-5-6-8-13(12)17(20)22/h9,14-15H,5-8,10H2,1-4H3

InChIKey

CXBMCYHAMVGWJQ-UHFFFAOYSA-N

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Allgemeine Beschreibung

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ. Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate. Download your certificate at: http://www.sigma-aldrich.com.

Tetramethrin, a type I pyrethroid, is used worldwide to protect crops and mammals from a variety of pests such as flies, fleas, mosquitoes, headlice, and mites. Tetramethrin is a synthetic pyrethroid insecticide, that binds to voltage-gated sodium channels of insect nerves and prevents its transition from an activated (ion-conducting) to an inactivated (non-conducting) state. This leads to a permanent depolarization of axonal membranes, causing paralysis and death of an insect.


Tetramethrin is not approved for use in the EU.
The maximum residue limits (MRLs) of pyrethroids compounds in fruits and fruit juices have been set at 0.02 to 0.5 mg/kg in China (GB2763-2019), and 0.02 to 0.3 mg/kg in European Union (EU) (Part A of Annex to Reg. 396/2005), respectively.

Anwendung

It is intended to be used as a certified reference material (CRM) for calibration in chromatography and other analytical techniques. Tetramethrin in CRM may also find its use as described below:
  • Study of Estrogenic activity of tetramethrin in uterine CaBP-9k gene expression and a uterotrophic assay, and androgenic activity in Hershberger assay
  • To synthesize bis-dihydroxyboron fluorescein complexes for developing a ratiometric fluorescence probe used in the direct detection of pyrethroid residues in fruit juices
  • Separation of the four isomers of tetramethrin with ecotoxicity test and quantitative analysis in agrochemical formulations using chiral electrokinetic chromatography methodology
  • Residual detection of acetanilide, pentylenetetrazole, phenacetin, and tetramethrin in porcine muscle, pasteurized milk, and eggs by liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method
  • To test glucocorticoid-like activity of propylparaben, butylparaben, diethylhexyl phthalate, and tetramethrin mixtures in different combinations at real human exposure levels

Rechtliche Hinweise

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - STOT SE 2 Inhalation

Zielorgane

Nervous system

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2


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Analysenzertifikate (COA)

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M Greño et al.
The Science of the total environment, 800, 149496-149496 (2021-08-14)
The separation of the four isomers of tetramethrin was performed for the first time using a cyclodextrin-micellar electrokinetic chromatography methodology. Using sodium deoxycholate and 2-hydroxypropyl-β-CD as chiral selectors, tetramethrin isomers were separated with resolution values of 1.7 and 1.1 for
Linda M Field et al.
European biophysics journal : EBJ, 46(7), 675-679 (2017-01-11)
The pyrethroid insecticides are a very successful group of compounds that have been used extensively for the control of arthropod pests of agricultural crops and vectors of animal and human disease. Unfortunately, this has led to the development of resistance
Dan Zhang et al.
Environmental monitoring and assessment, 188(6), 348-348 (2016-05-15)
A liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method was developed for monitoring and detection of four different drugs, namely acetanilide, pentylenetetrazole, phenacetin, and tetramethrin in porcine muscle, pasteurized milk, and table egg samples. For acetanilide and pentylenetetrazole, the samples
An efficiently ratiometric fluorescent probe based on bis-dihydroxyboron fluorescein complexes for detection of pyrethroid residues in fruit juices
Fang F, et al.
Microchemical Journal, Devoted to the Application of Microtechniques in All Branches of Science, 106954 null
Dan Zhang et al.
Environmental monitoring and assessment, 188(6), 348-348 (2016-05-15)
A liquid chromatography-electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS) method was developed for monitoring and detection of four different drugs, namely acetanilide, pentylenetetrazole, phenacetin, and tetramethrin in porcine muscle, pasteurized milk, and table egg samples. For acetanilide and pentylenetetrazole, the samples

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