67731

N-Nitrosomorpholin

analytical standard

• Synonym(e): Nitrosomorpholin, NMOR
• Empirische Formel (Hill-System): C₄H₈N₂O₂
• CAS-Nummer: 59-89-2
• Molekulargewicht: 116.12
• UNSPSC Code: 12352200
• MDL number: MFCD00039710
• NACRES: NA.24

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: Manufactured by: Sigma-Aldrich Production GmbH, Switzerland
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): cosmetics; food and beverages
• format: neat
• storage temp.: 2-8°C
• SMILES string: O=NN1CCOCC1
• InChI: 1S/C4H8N2O2/c7-5-6-1-3-8-4-2-6/h1-4H2
• InChI key: ZKXDGKXYMTYWTB-UHFFFAOYSA-N

Beschreibung

General description

Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity.


N-Nitrosomorpholin (CAS 59-89-2) is a non‑intentionally added substance (NIAS), typically formed by nitrosation of secondary amines in polymers, adhesives, inks, or elastomers. It is not deliberately used as a monomer or additive; occurrences are trace‑level and process‑dependent. Analytical testing focuses on trace identification and quantification, root‑cause analysis, and trend monitoring under worst‑case time/temperature/simulant conditions to support risk assessment and compliance. This analytical standard is utilized in chromatographic and spectrometric techniques for the detectionof nitrosamines in chemical, pharmaceutical, food and environmental matrices.

Discover our portfolio of nitrosamine reference materials

Application

N-Nitrosomorpholine may be used as an analytical reference standard for the determination of nitrosamines in drinking water using ultra-high-pressure liquid chromatography coupled with tandem mass spectrometry (UHPLC/MS/MS).

Analysis Note

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Zielorgane: Liver
• Gefahrencodes: H301,H341,H350,H372
• Hazard Classifications: Acute Tox. 3 Oral - Carc. 1B - Muta. 2 - STOT RE 1
• Sicherheitshinweise: P202 - P260 - P264 - P280 - P301 + P310 - P405