47775

Menadion (K3)

analytical standard

• Synonym(e): Menadion, 2-Methyl-1,4-naphthochinon, Vitamin K₃
• Empirische Formel (Hill-System): C₁₁H₈O₂
• CAS-Nummer: 58-27-5
• Molekulargewicht: 172.18
• EC Number: 200-372-6
• UNSPSC Code: 12164500
• PubChem Substance ID: 24871411
• Beilstein/REAXYS Number: 1908453
• MDL number: MFCD00001681
• NACRES: NA.24

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• CofA: current certificate can be downloaded
• feature: standard type fat soluble vitamin
• packaging: ampule of 1000 mg
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• mp: 105-107 °C (lit.)
• application(s): pharmaceutical (small molecule); vitamins, nutraceuticals, and natural products
• format: neat
• storage temp.: 2-30°C
• SMILES string: CC1=CC(=O)c2ccccc2C1=O
• InChI: 1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
• InChI key: MJVAVZPDRWSRRC-UHFFFAOYSA-N
• Gene Information: human ... NQO1(1728)

Beschreibung

General description

Menadione is a prothrombogenic compound and belongs to the Vitamin K class of compounds, which are necessary for the biosynthesis of prothrombin and other blood clotting factors. It is used as a model quinone in cell culture and in vivo investigations. It is obtained as a catabolic product of phylloquinone and circulating precursor of tissue menaquinone-4 in rats.

Menadione (K3) is a fat-soluble vitamin precursor and catabolic product of oral phylloquinone (vitamin k1) in the intestine.

Application

Menadione (K3) may be used as an analytical reference standard for the quantification of the analyte in biological fluids using liquid chromatography technique.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Sicherheitshinweise

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H317,H319,H335,H410
• pcodes: P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves