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Merck

T8657

Trichloressigsäure

suitable for electrophoresis, suitable for fixing solution (for IEF and PAGE gels), ≥99%

Synonym(e):

TCA

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250 G

€ 245,00

500 G

€ 447,00

1 KG

€ 786,00

€ 245,00


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Über diesen Artikel

Lineare Formel:
Cl3CCOOH
CAS-Nummer:
Molekulargewicht:
163.39
UNSPSC Code:
41105319
NACRES:
NB.22
PubChem Substance ID:
EC Number:
200-927-2
Beilstein/REAXYS Number:
970119
MDL number:
Assay:
≥99%
Form:
powder or flakes (or crystals)
Grade:
electrophoresis grade

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grade

electrophoresis grade

vapor density

<1 (vs air)

vapor pressure

1 mmHg ( 51 °C)

assay

≥99%

form

powder or flakes (or crystals)

technique(s)

electrophoresis: suitable

turbidity

≤3 NTU (1 g/ml)

refractive index

n20/D 1.62 (lit.)

bp

196 °C (lit.)

mp

54-58 °C (lit.)

solubility

water: 1 g/mL, clear, colorless

density

1.62 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): ≤0.001%, nitrate (NO3-): ≤0.002%, phosphate (PO43-): ≤5 ppm, sulfate (SO42-): ≤0.02%

cation traces

Fe: ≤0.0005%, heavy metals (as Pb): ≤0.002%

suitability

suitable for fixing solution (for IEF and PAGE gels)

application(s)

cell analysis

storage temp.

2-8°C

SMILES string

OC(=O)C(Cl)(Cl)Cl

InChI

1S/C2HCl3O2/c3-2(4,5)1(6)7/h(H,6,7)

InChI key

YNJBWRMUSHSURL-UHFFFAOYSA-N

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1 of 4

Dieser Artikel
T48858.22342T0699
assay

≥99%

assay

≥99.0% (titration)

assay

≥98% (acidimetric)

assay

-

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder or flakes (or crystals)

form

powder or crystals

form

solid

form

liquid

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

2-30°C

storage temp.

-

solubility

water: 1 g/mL, clear, colorless

solubility

H2O: 1 g/10 mL

solubility

1300 g/L

solubility

-

vapor density

<1 (vs air)

vapor density

<1 (vs air)

vapor density

-

vapor density

-

General description

Trichloroacetic acid (TCA) is produced during the chlorination of water comprising natural organic material. It is a novel reagent used in clinical laboratories for deproteinization of body fluids. In addition, TCA is also used in the treatment of genital warts and acne scars.

Application

Traditionell zur Fällung von Proteinen verwendet. Zur Bestimmung der Proteinkonzentration durch quantitative Fällung. Zum Entkalken und als Fixationsmittel in der Mikroskopie verwendet.
Trichloroacetic acid has been used:
  • for hydrolysis of DNA isolated from the cell
  • for precipitation of glutathione isolated from seminal plasma
  • as a fixative in microscopy

pictograms

CorrosionEnvironment

signalword

Danger

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1A

wgk

WGK 2

flash_point_f

>235.4 °F - closed cup

flash_point_c

> 113 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Lagerklasse

8A - Combustible corrosive hazardous materials


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Analysenzertifikate (COA)

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Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Focal treatment of acne scars with trichloroacetic acid: chemical reconstruction of skin scars method
Lee J, et al.
Dermatologic Surgery : Official Publication For American Society For Dermatologic Surgery [Et Al.], 28(11), 1017-1021 (2002)
Determination of total protein in spinal fluid with sulphosalicylic acid and trichloroacetic acid
Meulemans O
Clinica Chimica Acta; International Journal of Clinical Chemistry, 5(5), 757-761 (1960)
Quantitation of DNA fragmentation with diphenylamine
Boraschi D and Maurizi G
Apoptosis-a laboratory manual of experimental methods, 153-161 (1998)
Teratogenic activity of trichloroacetic acid in the rat
Smith MK, et al.
Teratology, 40(5), 445-451 (1989)
Atmospheric pressure pulsed plasma induces cell death in photosynthetic organs via intracellularly generated ROS
Seol Y, et al.
Scientific reports, 7(1), 589-589 (2017)

Global Trade Item Number

SKUGTIN
T8657-500G04061837379529
T8657-1KG04061826759233
T8657-250G04061835550333

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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