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T3516

Thioflavin T

Powder

Synonym(e):

Basic Yellow 1, Thioflavin T

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Ihnen/SKUVerfügbarkeitPreis
5 g
Warenkorb auf Verfügbarkeit prüfen
€ 61,60
25 g
Warenkorb auf Verfügbarkeit prüfen
€ 118,00

Über diesen Artikel

Empirische Formel (Hill-System):
C17H19ClN2S
CAS-Nummer:
Molekulargewicht:
318.86
UNSPSC Code:
12171500
NACRES:
NA.47
PubChem Substance ID:
EC Number:
219-228-9
MDL number:
Beilstein/REAXYS Number:
3922452
Colour Index Number:
49005

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Produktname

Thioflavin T, used as stain for amyloid

Quality Segment

form

powder

composition

Dye content, ≥65%

solubility

methanol: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Cl-].CN(C)c1ccc(cc1)-c2sc3cc(C)ccc3[n+]2C

InChI

1S/C17H19N2S.ClH/c1-12-5-10-15-16(11-12)20-17(19(15)4)13-6-8-14(9-7-13)18(2)3;/h5-11H,1-4H3;1H/q+1;/p-1

InChI key

JADVWWSKYZXRGX-UHFFFAOYSA-M

General description

Thioflavin T is a benzothiazole dye that increases in fluorescence upon binding to amyloid. Thioflavin T has been used in histology and for protein characterization.

Application

Thioflavin T has been used to identify the presence of amyloid fibrils in samples.

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Dieser Artikel
596200T1892F6377
description

used as stain for amyloid

description

A cell-permeable benzothiazole dye that exhibits enhanced fluorescence upon binding to amyloid fibrils.

description

practical grade

description

used as fluorescent tracer

form

powder

form

solid

form

powder

form

powder

solubility

methanol: 1 mg/mL

solubility

water: 5 mg/mL

solubility

ethanol: water (1:1): 1 mg/mL

solubility

H2O: 1 mg/mL

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

-

application(s)

diagnostic assay manufacturing
hematology
histology

application(s)

diagnostic assay manufacturing
hematology
histology

composition

Dye content, ≥65%

composition

-

composition

-

composition

-

storage temp.

room temp

storage temp.

15-25°C

storage temp.

room temp

storage temp.

room temp

Quality Level

200

Quality Level

100

Quality Level

200

Quality Level

200


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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Sens. 1

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Analysenzertifikate (COA)

Lot/Batch Number

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Questions

1–2 of 2 Questions  
  1. How about the purity of this product?

    1 answer
    1. The purity of this material is indicated by the dye content. The minimum dye content of this product is 65%. A brief review of recent lots indicates that 85 - 90% dye content is typical. Please see the link below to review additional information available in the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/543/093/t3516pis.pdf

      Helpful?

  2. How do you reconsititute the powder?

    1 answer
    1. As described in the product data sheet, the product is soluble in methanol at 1mg/mL (0.1% w/v).
      Please see the product data sheet for additional solubility and handling recommendations: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/543/093/t3516pis.pdf

      Helpful?

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