SRP8032

IL-1 Receptor Type I (human): FC (human)

recombinant, expressed in HEK 293 cells, >95% (SDS-PAGE)

• Synonym(e): Interleukin-1 receptor alpha, Interleukin-1 receptor type I, RI, Serpin F1
• NACRES: NA.32
• UNSPSC Code: 12352200
• Form: lyophilized
• Assay: >95% (SDS-PAGE)
• Biological source: human
• Recombinant: expressed in HEK 293 cells
• Mol wt: ~80 kDa by SDS-PAGE

Eigenschaften

• biological source: human
• recombinant: expressed in HEK 293 cells
• assay: >95% (SDS-PAGE)
• form: lyophilized
• mol wt: ~80 kDa by SDS-PAGE
• packaging: pkg of 50 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: <0.1 EU/μg endotoxin, tested
• color: white
• UniProt accession no.: P14778
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... IL1R1(3554)

Beschreibung

General description

IL-1RI is the receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88, and IRAK1 or IRAK2.

Physical form

Lyophilized from PBS.

Preparation Note

Reconstitute with 50 μL deionized water.

Other Notes

Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable