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SRP6516

Albumin aus Humanplasma

≥95% (SDS-PAGE)

Synonym(e):

Albumin protein, human Albumin, human Albumin protein, human plasma, human plasma Albumin proteinHSA, native Albumin, native Albumin protein

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Über diesen Artikel

UNSPSC Code:
12352202
EC Number:
232-692-7
NACRES:
NA.32
Biological source:
human
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized


biological source

human

assay

≥95% (SDS-PAGE)

form

lyophilized

mol wt

66 kDa

packaging

pkg of 1G

color

beige

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... ALB(213)

General description

Human albumin is encoded by ALB gene that is mapped to human chromosome 4q. The gene is developmentally regulated and is synthesized by the liver. The encoded protein has a molar mass of 65,000 Da and consists of a single polypeptide chain of 585 amino acids.

Application

Albumin has been used in ion exchange chromatography to compare the albumin isolated from whole human plasma. It has been used to bind to phage clones in phage binding assay.

Biochem/physiol Actions

Human albumin is a globular unglycosylated serum protein that makes up for more than half of the total plasma or serum proteins. It functions in the maintenance of COP (cellular oncotic pressure). It binds to hydrophobic organic anions such as, bilirubin, long-chain fatty acids and haematin and some cations such as magnesium and calcium. It also serves as a secondary or tertiary carrier for steroids, vitamin D and thyroxine. It is involved in the catabolism of prostaglandins and metabolism of certain endogenous substances, such as lipids, and eicosanoids. It acts as a plasma buffer and scavenges oxygen free radicals, thus reducing the pathological effects of certain inflammatory diseases. Mutation in the gene coding for albumin leads to familial dysalbuminaemic hyperthyroidism.

Physical form

Lyophilized as a salt free solid.


Piktogramme

Health hazard

Signalwort

Danger

Gefahrencodes

Lagerklasse

11 - Combustible Solids

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Sicherheitshinweise

Hazard Classifications

Resp. Sens. 1



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Questions

  1. Is it acceptable to store this product at room temperature for approximately 24 hours? Would this affect the product's stability or performance?

    1 answer
    1. The recommended storage temperature for this product is -20°C. While this Human Serum Albumin (HSA) product ships on ice, other HSA product do ship at ambient temperature and are relatively stable at room temperature. A single 24-hour exposure at room temperature is unlikely to substantially impact the integrity of the product.

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