SRP3231

PF-4 from mouse

≥98% (SDS-PAGE & HPLC), recombinant, expressed in E. coli, lyophilized, suitable for cell culture

• Synonym(e): CXCL4, Ironplact, Oncostatin A, Platelet Factor-4
• UNSPSC Code: 12352202
• NACRES: NA.32
• Biological source: mouse
• Recombinant: expressed in E. coli
• Assay: ≥98% (HPLC), ≥98% (SDS-PAGE)
• Form: lyophilized
• Mol wt: 8.2 kDa
• Impurities: <0.1 EU/μg endotoxin, tested

Eigenschaften

• Produktname: PF-4 from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture
• biological source: mouse
• recombinant: expressed in E. coli
• assay: ≥98% (HPLC), ≥98% (SDS-PAGE)
• form: lyophilized
• potency: 10.0-100.0 ng/mL
• mol wt: 8.2 kDa
• packaging: pkg of 1 mg, pkg of 20 μg
• technique(s): cell culture | mammalian: suitable
• impurities: <0.1 EU/μg endotoxin, tested
• color: white
• UniProt accession no.: Q9Z126
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: mouse ... PF4(56744)

Beschreibung

General description

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the a-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis. Recombinant murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Biochem/physiol Actions

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the a-granules of platelets. Recombinant murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

Other Notes

VTSAGPEESD GDLSCVCVKT ISSGIHLKHI TSLEVIKAGR HCAVPQLIAT LKNGRKICLD RQAPLYKKVI KKILES

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable