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SRP3016

BMP-4 human

Name: BMP-4 human
Brand: SIGMA
Price: 359 EUR

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture

Synonym(e):

BMP-2B, DVR4

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Größe/SKU	Verfügbarkeit	Preis
10 μg	Versand in der Regel in 2 Wochen.	€ 359,00

Über diesen Artikel

NACRES:

NA.32

UNSPSC Code:

12352202

€ 359,00

Versand in der Regel in 2 Wochen.

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Unterstützung erhalten

Eigenschaften

biological source

human

recombinant

expressed in E. coli

assay

≥98% (HPLC), ≥98% (SDS-PAGE)

form

lyophilized

potency

5-10 ng/mL ED₅₀

mol wt

23.8 kDa

packaging

pkg of 10 μg

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 EU/μg endotoxin, tested

UniProt accession no.

P12644

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... BMP4(652)

Beschreibung

General description

Recombinant human Bone Morphogenetic Protein‑4 (BMP‑4) is a homodimeric signaling protein expressed in E. coli and supplied as a lyophilized powder for mammalian cell culture research in vitro.

Application

Recombinant BMP‑4 has been used in mammalian cell culture research applications involving stem cell differentiation and lineage‑specific in vitro model systems.

Biochem/physiol Actions

Bone Morphogenetic Protein‑4 (BMP‑4) is a TGF‑β family growth factor that mediates cellular responses through SMAD‑dependent signaling. It is involved in diverse physiological processes including development and maintenance of bone and cartilage during both pre- and postnatal life.

Physical form

Lyophilized with no additives.

Preparation Note

Centrifuge the vial prior to opening. Reconstitute in 5 mM HCl, pH 3.0 to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8° C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20° C to -80° C.

Other Notes

KKNKNCRRHS LYVDFSDVGW NDWIVAPPGY QAFYCHGDCP FPLADHLNST NHAIVQTLVN SVNSSIPKAC CVPTELSAIS MLYLDEYDKV VLKNYQEMVV EGCGCR

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Dieser Artikel	B2680	SRP3298	GF167
Sigma-Aldrich SRP3016 BMP-4 human	Sigma-Aldrich B2680 Bone Morphogenetic Protein 4 human	Sigma-Aldrich SRP3298 BMP-4 mouse	Sigma-Aldrich GF167 BMP-4 Protein, Human Recombinant
description recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture	description >95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture	description recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)	description The Bone morphogenetic protein 4 (or BMP-4 protein) is a TGFβ superfamily ligand that is widely expressed from early embryogenesis through adulthood.
recombinant expressed in E. coli	recombinant expressed in NSO cells	recombinant expressed in E. coli	recombinant -
assay ≥98% (SDS-PAGE), ≥98% (HPLC)	assay >95% (SDS-PAGE)	assay ≥98% (HPLC), ≥98% (SDS-PAGE)	assay >97% (SDS-PAGE and HPLC)
biological source human	biological source human	biological source mouse	biological source -
technique(s) cell culture \| mammalian: suitable	technique(s) cell culture \| mammalian: suitable	technique(s) -	technique(s) -
form lyophilized	form lyophilized powder	form lyophilized	form -
impurities <0.1 EU/μg endotoxin, tested	impurities <0.01 EU/μg Endotoxin level (LAL test)	impurities <0.1 EU/μg endotoxin, tested	impurities <0.1 μg/mg protein endotoxin (<1EU/μg)

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Lagerklasse

11 - Combustible Solids

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WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)