Human UTX, also known as KDM6A (GenBank Accession No. NM_021140) amino-acids 1-1401 with C-terminal FLAG-tag, MW = 155 kDa, expressed in Sf9 cells via a Baculovirus expression system.
The trithorax and the polycomb group proteins are chromatin modifiers, which play a key role in the epigenetic regulation of development, differentiation and maintenance of cell fates. The polycomb repressive complex 2 (PRC2) mediates transcriptional repression by catalysing the di-
Human molecular genetics, 7(4), 737-742 (1998-05-16)
We recently have identified a ubiquitously transcribed mouse Y chromosome gene, Uty , which encodes a tetratricopeptide repeat (TPR) protein. A peptide derived from the UTY protein confers H-Y antigenicity on male cells. Here we report the characterization of a
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