SML3823

KCI807

≥98% (HPLC)

• Synonym(e): 5,3’-Dihydroxyflavone, 5-Hydroxy-2-(3-hydroxyphenyl)-4H-1-benzopyran-4-one
• Empirische Formel (Hill-System): C₁₅H₁₀O₄
• CAS-Nummer: 6665-68-5
• Molekulargewicht: 254.24
• UNSPSC Code: 51111800
• NACRES: NA.77
• MDL number: MFCD00143394
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: 0.2 mg/mL (DMSO:EtOH (2:1),clear, warmed, clear colorless solution)
• storage temp.: room temp
• SMILES string: [o]1c2c([c](cc1c3cc(ccc3)O)=O)c(ccc2)O
• InChI key: SZMQXDYEGKRZDG-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction

KCI807 is a cell penetrant, selective and potent inhibitor of the androgen receptor (AR)-ELK1 interaction. KCI807 interrupts association of the androgen receptor (AR) with transcription activator ELK1 (ETS family transcription factor ELK1). It potently suppresses growth of enzalutamide-resistant prostate cancer tumor xenografts in rodents.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable