SML3681

ATM-3507

≥95% (HPLC)

• Synonym(e): ATM 3507, [3-​[[2,​3-​Dimethyl-​1-​[3-​(4-​methyl-​1-​piperazinyl)​propyl]​-​1H-​indol-​5-​yl]​oxy]​phenyl]​[4-​[2-​(4-​fluorophenyl)​ethyl]​-​1-​piperazinyl]​-methanone
• Empirische Formel (Hill-System): C₃₇H₄₆FN₅O₂
• CAS-Nummer: 1861449-70-8
• Molekulargewicht: 611.79
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD31657327
• Assay: ≥95% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥95% (HPLC)
• form: powder
• color: , Colorless to light brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

ATM-3507 is a potent anti-tropomyosin agent that disables Tpm3.1 containing actin filaments. It exhibits potent cytotoxic activity against multiple neuroblastoma cancer cell lines. ATM-3507 sensitizes cancer cells to anti-microtubule agents. ATM-3507 significantly prolonged mitotic arrest induced by anti-microtubule agent vinorelbine.

Potent anti-tropomyosin agent that disables Tpm3.1 containing actin filaments

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable