SML3309

DN01

≥98% (HPLC)

• Synonym(e): 4-(4-((Dimethylamino)methyl)-2,6-dimethoxyphenyl)-7-fluoro-2-methylisoquinolin-1(2H)-one
• Empirische Formel (Hill-System): C₂₁H₂₃FN₂O₃
• CAS-Nummer: 2965690-32-6
• Molekulargewicht: 370.42
• NACRES: NA.77
• UNSPSC Code: 12352200
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: , White to light brown
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: -10 to -25°C

Beschreibung

Biochem/physiol Actions

DN01 is a potent and selective BRD8 first bromodomain inhibitor (BRD8(1) IC50 = 12 nM; BRD4(1) & BRD9 IC50 ≥10 μM) that serves as a useful chemical probe for the selective engagement of BRD8 and enrichment of native NuA4 complexes.

Potent and selective BRD8 first bromodomain inhibitor for probing the engagement of BRD8 and enrichment of native NuA4 complexes.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable