This product is provided in its free-amine form without a counter ion, e.g., an anion bound to it.
Fortfahren mit
SML3257
Demethyleneberberine
≥98% (HPLC)
Synonym(e):
5,6-Dihydro-2,3-dihydroxy-9,10-dimethoxy-dibenzo[a,g]quinolizinium, 7,8,13,13a-Tetradehydro-2,3-dihydroxy-9,10-dimethoxy-berbinium, Demethylene-berberine
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Über diesen Artikel
Empirische Formel (Hill-System):
C19H18NO4
CAS-Nummer:
Molekulargewicht:
324.35
UNSPSC Code:
12352210
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Preise und Verfügbarkeit sind derzeit nicht verfügbar.
Technischer Dienst
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Unterstützung erhaltenQuality Segment
assay
≥98% (HPLC)
form
powder
color
, White to very dark grey
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
SMILES string
[n+]21c(cc4c(c2)c(c(cc4)OC)OC)c3c(cc(c(c3)O)O)CC1
InChI
1S/C19H17NO4/c1-23-18-4-3-11-7-15-13-9-17(22)16(21)8-12(13)5-6-20(15)10-14(11)19(18)24-2/h3-4,7-10,22H,5-6H2,1-2H3/p+1
InChI key
HVTCKKMWZDDWOY-UHFFFAOYSA-O
Biochem/physiol Actions
Demethyleneberberine, a berberine metabolite, is a mitochondria-targeted antioxidant isolated from Cortex Phellodendri chinensis that exhibits multiple pharmacological activities including anti-microbial, anti-inflammatory, anti-diarrhea and anti-cancer. Demethyleneberberine alleviates ethanol-dependent oxidative stress by suppression of cytochrome CYP2E1 (P450 2E1), hypoxia inducible factor α (HIF-1α) and inducible nitric oxide synthase (iNOS). It appears that demethyleneberberine attenuates non-alcoholic fatty liver disease (NAFLD) through activation of AMPK.
Mitochondrially targeted antioxidant
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Dieser Artikel | |||
|---|---|---|---|
| description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) | description ≥98% (HPLC) |
| form powder | form powder | form powder | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C | storage temp. -10 to -25°C |
| solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (Warmed) | solubility DMSO: 2 mg/mL, clear |
| color , White to very dark grey | color white to beige | color , Red to very dark purple | color white to beige |
Lagerklasse
11 - Combustible Solids
Was ist los?
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Hi, I would like to ask if your product Demethyleneberberine (CAS: 25459-91-0) has anionic binding? If so, what anion is it? Is it chloride? Many thanks!
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Helpful?
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