SML2808

Sparsentan

≥98% (HPLC), Angiotensin II receptor antagonist, powder

• Synonym(e): 2-[4-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-2-(ethoxymethyl)phenyl]-N-(4,5-dimethyl-1,2-oxazol-3-yl)benzenesulfonamide, 4′-[(2-Butyl-4-oxo-1,3-diazaspiro[4.4]non-1-en-3-yl)methyl]-N-(4,5-dimethyl-3-isoxazolyl)-2′-(ethoxymethyl)[1,1′-biphenyl]-2-sulfonamide, BMS-346567, BMS346567, RE-021
• Empirische Formel (Hill-System): C₃₂H₄₀N₄O₅S
• CAS-Nummer: 254740-64-2
• Molekulargewicht: 592.75
• UNSPSC Code: 12352200
• NACRES: NA.77
• MDL number: MFCD16628036
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Sparsentan, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: [S](=O)(=O)(Nc5n[o]c(c5C)C)c1c(cccc1)c2c(cc(cc2)CN3C(=O)C4(NC3=CCCC)CCCC4)COCC
• InChI key: OIBXMWCQTPVHKR-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Sparsentan (BMS346567) is an orally available and highly potent dual antagonist of angiotensin II AT1 receptor and endothelin A ETA receptor. It is an analog of BMS-248360 that is orally available in rats and higher species.

orally available dual angiotensin II and endothelin A receptor antagonist

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable