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SML2370

Dabigatran

≥95% (HPLC), Nonpeptide direct thrombin inhibitor, powder

Dabigatran

Synonym(e):

BIBR-953, N-[[2-[[[4-(Aminoiminomethyl)phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-β-alanine

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Ihnen/SKUVerfügbarkeitPreis
5 mg
Warenkorb auf Verfügbarkeit prüfen
€ 106,00
25 mg
Warenkorb auf Verfügbarkeit prüfen
€ 338,00

Über diesen Artikel

Empirische Formel (Hill-System):
C25H25N7O3
CAS-Nummer:
211914-51-1
Molekulargewicht:
471.51
NACRES:
NA.77
UNSPSC Code:
12352200
MDL number:
MFCD09837830
Assay:
≥95% (HPLC)
Form:
powder

€ 106,00

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Unterstützung erhalten

Produktname

Dabigatran, ≥95% (HPLC)

assay

≥95% (HPLC)

form

powder

color

white to beige

solubility

0.1 M HCl: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

N=C(N)C(C=C1)=CC=C1NCC(N2C)=NC3=C2C=CC(C(N(CCC(O)=O)C4=NC=CC=C4)=O)=C3

InChI

1S/C25H25N7O3/c1-31-20-10-7-17(25(35)32(13-11-23(33)34)21-4-2-3-12-28-21)14-19(20)30-22(31)15-29-18-8-5-16(6-9-18)24(26)27/h2-10,12,14,29H,11,13,15H2,1H3,(H3,26,27)(H,33,34)

InChI key

YBSJFWOBGCMAKL-UHFFFAOYSA-N

Biochem/physiol Actions

Dabigatran is a nonpeptide direct thrombin inhibitor. It is an anticoagulant that functions by directly inhibiting both free and fibrin-bound thrombin. Dabigatron has been shown to prevent strokes in those with atrial fibrillation not caused by heart valve issues.
Nonpeptide, direct thrombin inhibitor

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Dieser Artikel
SML2351SML1086SML1762
Dabigatran ≥95% (HPLC)

Sigma-Aldrich

SML2370

Dabigatran

Dabigatran etexilate ≥98% (HPLC)

Sigma-Aldrich

SML2351

Dabigatran etexilate

BX-912 ≥95% (HPLC)

Sigma-Aldrich

SML1086

BX-912

SI-2 ≥98% (HPLC)

Sigma-Aldrich

SML1762

SI-2

form

powder

form

powder

form

powder

form

powder

assay

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥95% (HPLC)

assay

≥98% (HPLC)

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

2-8°C

solubility

0.1 M HCl: 2 mg/mL, clear

solubility

DMSO: 2 mg/mL, clear

solubility

DMSO: 10 mg/mL, clear

solubility

DMSO: 20 mg/mL, clear

color

white to beige

color

white to beige

color

white to beige

color

, light yellow to dark orange

Lagerklasse

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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1 Review This action will navigate to reviews.

Questions

  1. Hello, How to reconstitute dabigatran? Thank you

    1 answer

    1. This product can be solubilized in 0.1M HCl at > 2.0 mg/ml. The exact solubility of this product will be listed on the lot-specific Certificate of Analysis.

      Please navigate to the DOCUMENTATION section of the Product Detail Page to access a sample or lot specific Certificate under ‘Certificate of Analysis’:
      https://www.sigmaaldrich.com/product/sigma/sml2370#product-documentation

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Reviews

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  1. Geneva
    • Review 1
    • Votes 0
    1 out of 5 stars.

    Too large bootle for 5 mg bottle

    Placing a 5 mg powder in a large glass bottle is really inconvenient. The power cannot be taken out at all.

    Helpful?

    1. Response from Merck KGaA:

      Thank you for your review.
      SML2370 is supplied in a large enough vial for the product to be reconstituted in it. This allows the full amount to be reconstituted without losing powder while transferring. Please do not transfer powder out of the vial before reconstitution.
      We encourage customers who experience problems with our products to contact us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.