SML2141

Solifenacinsuccinat

≥98% (HPLC), muscarinic M3 receptors inhibitor, powder

• Synonym(e): (1S)-(3R)-1-azabicyclo[2.2.2]oct-3-yl 3,4­dihydro-1-phenyl-2(1H)-iso-quinolinecarboxylate succinate, YM905
• Empirische Formel (Hill-System): C₂₃H₂₆N₂O₂ · C₄H₆O₄
• CAS-Nummer: 242478-38-2
• Molekulargewicht: 480.55
• NACRES: NA.77
• UNSPSC Code: 12352200
• MDL number: MFCD00954234
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Produktname: Solifenacinsuccinat, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D +35 to +45°, c = 1 in H₂O
• storage condition: desiccated
• color: white to beige
• solubility: H₂O: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: OC(CCC(O)=O)=O.O=C(O[C@H]1CN2CCC1CC2)N3[C@@H](C4=CC=CC=C4)C5=CC=CC=C5CC3
• InChI: 1S/C23H26N2O2.C4H6O4/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19;5-3(6)1-2-4(7)8/h1-9,18,21-22H,10-16H2;1-2H2,(H,5,6)(H,7,8)/t21?,22-;/m0./s1
• InChI key: RXZMMZZRUPYENV-DZSUWJOWSA-N

Beschreibung

Biochem/physiol Actions

Solifenacin succinate (SOL) blocks the cholinergic signals to M3 receptors by inhibiting the muscarinic M3 receptors in the bladder. This action prevents the contractions of the detrusor muscles in the urinary bladder wall, leading to relaxing the bladder as well as decreasing urinary urgency and nocturia. Thus, SOL is a widely used antimuscarinic agent for treating the contraction of the overactive bladder.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Warning
• Gefahrencodes: H361d
• Sicherheitshinweise: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable