SML2032

Win6mer trifluoroacetate salt

≥98% (HPLC)

• Synonym(e): Ac-ARTEVY-NH2 trifluouroaceate salt
• Empirische Formel (Hill-System): C₃₄H₅₄N₁₀O₁₁ · xC₂HF₃O₂
• CAS-Nummer: 2222444-20-2
• Molekulargewicht: 778.85 (free base basis)
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: film (Clear)

Eigenschaften

• assay: ≥98% (HPLC)
• form: film (Clear)
• color: white to off-white
• shipped in: wet ice
• storage temp.: −20°C
• SMILES string: C[C@H](NC(C)=O)C(N[C@H](C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC1=CC=C(C=C1)O)=O)C(C)C)=O)CCC(O)=O)=O)([H])[C@H](O)C)=O)CCCNC(N)=N)=O
• InChI: 1S/C34H54N10O11/c1-16(2)26(32(54)42-24(28(35)50)15-20-8-10-21(47)11-9-20)43-31(53)23(12-13-25(48)49)41-33(55)27(18(4)45)44-30(52)22(7-6-14-38-34(36)37)40-29(51)17(3)39-19(5)46/h8-11,16-18,22-24,26-27,45,47H,6-7,12-15H2,1-5H3,(H2,35,50)(H,39,46)(H,40,51)(H
• InChI key: DYNVFAUYAHJESK-NGPBCSSISA-N

Beschreibung

Biochem/physiol Actions

Win6mer is a potent and specific inhibitor of MLL1 and SETd1A histone H3 lysine 4 (H3K4) methyltransferase complexes that does not inhibit MLL2-4 or SETd1B complexes. Win6mer potently binds to WDR5 in a 310-helical conformation. It does not inhibit isolated SET domain activity.

potent and specific inhibitor of MLL1 and SETd1A histone H3 lysine 4 (H3K4) methyltransferase complexes

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable