SML1373

Angiotensin A trifluoroacetate salt

≥98% (HPLC)

• Synonym(e): ARVYIHPF trifluoroacetate salt, Ala-Arg-Val-Tyr-Ile-His-Pro-Phe trifluoroacetate salt, Ang A trifluoroacetate salt
• Empirische Formel (Hill-System): C₄₉H₇₁N₁₃O₁₀ · xC₂HF₃O₂
• CAS-Nummer: 51833-76-2
• Molekulargewicht: 1002.17 (free base basis)
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825825
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• color: white to off-white
• storage temp.: −20°C
• SMILES string: [H]N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@]([C@@H](C)CC)([H])C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)CC3=CN=CN3)=O)=O)CC(C=C4)=CC=C4O)=O)=O)=O)C
• InChI: 1S/C49H71N13O10/c1-6-28(4)40(46(69)58-36(24-32-25-53-26-55-32)47(70)62-21-11-15-38(62)44(67)59-37(48(71)72)23-30-12-8-7-9-13-30)61-43(66)35(22-31-16-18-33(63)19-17-31)57-45(68)39(27(2)3)60-42(65)34(56-41(64)29(5)50)14-10-20-54-49(51)52/h7-9,12-13,16-19,25-29,34-40,63H,6,10-11,14-15,20-24,50H2,1-5H3,(H,53,55)(H,56,64)(H,57,68)(H,58,69)(H,59,67)(H,60,65)(H,61,66)(H,71,72)(H4,51,52,54)/t28-,29-,34-,35-,36-,37-,38-,39-,40-/m0/s1
• InChI key: CHCOFDZSJYMQMX-NOQNJSOHSA-N

Beschreibung

Biochem/physiol Actions

Angiotensin A (Ang A) is an endogenous vasoconstrictor octapeptide. It is a derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid. Angiotensin A has similar affinity as Angiotensin II for AT1 and AT2 receptors with Ki values of 1.6 and 2.3 nM at AT1 and AT2 receptors.

Derivative of angiotensin II (Ang II) that differs from Ang II in having alanine instead of aspartic acid as the first amino acid; endogenous vasoconstrictor peptide.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable