SML1252

Treosulfan

≥98% (HPLC), Alkylating agent, powder

• Synonym(e): (2S,3S)-Butanetetraol 1,4-dimesylate, (2S,3S)-Threitol 1,4-bismethanesulfonate, L-Threitol 1,4-bis(methanesulfonate), NSC 39069, Threosulphan, Treosulphan
• Empirische Formel (Hill-System): C₆H₁₄O₈S₂
• CAS-Nummer: 299-75-2
• Molekulargewicht: 278.30
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Produktname: Treosulfan, ≥98% (HPLC)
• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• optical activity: [α]/D -4.9 to -5.9°, c = 1 in acetone
• color: white to beige
• solubility: H₂O: 5 mg/mL, clear
• storage temp.: −20°C
• SMILES string: [S](=O)(=O)(OCC(O)C(O)CO[S](=O)(=O)C)C
• InChI: 1S/C6H14O8S2/c1-15(9,10)13-3-5(7)6(8)4-14-16(2,11)12/h5-8H,3-4H2,1-2H3
• InChI key: YCPOZVAOBBQLRI-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Alkylating agent, anti-neoplastic agent

Treosulfan is a biofunctional alkylating agent.

Treosulfan is bifunctional alkylating agent.

Treosulfan/l-threitol-1,4-bis-methanesulfonate; dihydroxybusulfan; NSC 39069. It is a prodrug of a bifunctional alkylating cytotoxic agent. Treosulfan can be activated non-enzymatically to two active epoxides. It is used to treat ovarian cancer.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H340,H350,H361f
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Carc. 1A - Muta. 1B - Repr. 2
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable