SML1176

Carboxypyridostatin trifluoroacetate salt

≥95% (HPLC)

• Synonym(e): 4-[[[2,6-Bis[[[4-(2-aminoethoxy)-2-quinolinyl]amino]carbonyl]-4-pyridinyl]oxy]methyl]-1H-1,2,3-triazole-1-propanoic acid trifluoroacetate salt, carboxyPDS trifluoroacetate salt
• Empirische Formel (Hill-System): C₃₅H₃₄N₁₀O₇ · xC₂HF₃O₂
• CAS-Nummer: 1417638-60-8
• Molekulargewicht: 706.71 (free base basis)
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to light brown
• Löslichkeit: H₂O: 25 mg/mL, clear
• Lagertemp.: −20°C

Beschreibung

Anwendung

Carboxypyridostatin trifluoroacetate salt has been used in the study of translation, stimulated by DHX36 (DEAH-box helicase 36) binding at G-rich sites in mRNA untranslated regions.

Biochem./physiol. Wirkung

Carboxypyridostatin (carboxyPDS) selectively stabilizes RNA-containg G-quadruplex stuctures. Immunofluorescent staining of carboxyPDS treated cells using an anti G-quadruplex antibody reveals staining only in the cytoplasm and not the nucleus, demonstrating selectivity against DNA G-quadruplex structures.

Sonstige Hinweise

Light sensitive

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable