SML0500

GSK334429 hydrochloride

≥98% (HPLC)

• Synonym(e): 1-(1-Methylethyl)-4-((1-(6-(trifluoromethyl)-3-pyridinyl)-4-piperidinyl)carbonyl)hexahydro-1H-1,4-diazepine hydrochloride
• Empirische Formel (Hill-System): C₂₀H₂₉F₃N₄O · xHCl
• CAS-Nummer: 799558-94-4
• Molekulargewicht: 398.47 (free base basis)
• MDL-Nummer: MFCD22666404
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329825449
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: powder
• Lagerbedingungen: desiccated
• Farbe: white to beige
• Löslichkeit: H₂O: 5 mg/mL (clear solution)
• Lagertemp.: 2-8°C
• SMILES String: Cl.CC(C)N1CCCN(CC1)C(=O)C2CCN(CC2)c3ccc(nc3)C(F)(F)F
• InChI: 1S/C20H29F3N4O.ClH/c1-15(2)25-8-3-9-27(13-12-25)19(28)16-6-10-26(11-7-16)17-4-5-18(24-14-17)20(21,22)23;/h4-5,14-16H,3,6-13H2,1-2H3;1H
• InChIKey: RCZVWLOXPFGZDD-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

GSK334429 is a selective histamine H3 receptor antagonist.

GSK334429 is a selective histamine H3 receptor antagonist. H3 antagonists increase the release of brain histamine, ACh, NE and DA neurotransmitters that modulate cognitive processes. Studies look at their analgesic efffects including efficacy for neuropathic pain.

Leistungsmerkmale und Vorteile

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Sonstige Hinweise

Store desiccated; dry room.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable