SML0302

4-CMTB

≥98% (HPLC)

• Synonym(e): 4-Chloro-α-(1-methylethyl)-N-2-thiazolyl-benzeneacetamide
• Empirische Formel (Hill-System): C₁₄H₁₅ClN₂OS
• CAS-Nummer: 300851-67-6
• Molekulargewicht: 294.80
• NACRES: NA.77
• PubChem Substance ID: 329825307
• UNSPSC Code: 12352200
• MDL number: MFCD02666163
• Assay: ≥98% (HPLC)
• Form: powder
• Storage condition: desiccated

Eigenschaften

• Quality Segment: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white to beige
• solubility: DMSO: ≥10 mg/mL
• storage temp.: 2-8°C
• SMILES string: CC(C)C(C(=O)Nc1nccs1)c2ccc(Cl)cc2
• InChI: 1S/C14H15ClN2OS/c1-9(2)12(10-3-5-11(15)6-4-10)13(18)17-14-16-7-8-19-14/h3-9,12H,1-2H3,(H,16,17,18)
• InChI key: AZYDQCGCBQYFSE-UHFFFAOYSA-N

Beschreibung

Application

4-CMTB has been used as an allosteric agonist for the free fatty acid receptor 2 (FFAR2) in human lung carcinoma (A549) cells for cell viability assay and Influenza A virus (IAV) internalization studies.[1]

Biochem/physiol Actions

4-CMTB is a phenylacetamide compound that acts as an allosteric modulator for the activity of short-chain fatty acid ligand in the FFA2 receptor.[2]

4-CMTB is a potent allosteric agonist of FFA2.

4-CMTB is a potent allosteric agonist of free fatty acid receptor 2 (FFA2).

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable