SMB01061

Emetine

≥90% (LC/MS-ELSD)

• Synonym(e): (-)-Emetine
• Empirische Formel (Hill-System): C₂₉H₄₀N₂O₄
• CAS-Nummer: 483-18-1
• Molekulargewicht: 480.64
• UNSPSC Code: 12352205
• NACRES: NA.25
• MDL number: MFCD00242944

Eigenschaften

• biological source: plant
• assay: ≥90% (LC/MS-ELSD)
• form: solid
• mol wt: 480.64
• solubility: water: soluble
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: N21[C@@H](C[C@@H]([C@H](C2)CC)C[C@H]4NCCc5c4cc(c(c5)OC)OC)c3c(cc(c(c3)OC)OC)CC1
• InChI: 1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1
• InChI key: AUVVAXYIELKVAI-CKBKHPSWSA-N

Beschreibung

General description

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Application

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Biochem/physiol Actions

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.

Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Features and Benefits

• High quality compound suitable for multiple research applications
• Compatible with HPLC and mass spectrometry techniques

Other Notes

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Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable