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SMB00461

Sigma-Aldrich

Harmin -hydrochlorid

≥98% (HPLC)

Synonym(e):

7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole hydrochloride

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About This Item

Empirische Formel (Hill-System):
C13H12N2O · HCl
CAS-Nummer:
343-27-1
Molekulargewicht:
248.71
EG-Nummer:
206-443-8
MDL-Nummer:
MFCD00012641
UNSPSC-Code:
12352205
PubChem Substanz-ID:
329825025
NACRES:
NA.25

Qualitätsniveau

200

Assay

≥98% (HPLC)

Form

powder

Anwendung(en)

metabolomics
vitamins, nutraceuticals, and natural products

Lagertemp.

2-8°C

SMILES String

Cl.COc1ccc2c(c1)[nH]c3c(C)nccc23

InChI

1S/C13H12N2O.ClH/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13;/h3-7,15H,1-2H3;1H

InChIKey

VNPLYCKZIUTKJM-UHFFFAOYSA-N

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Allgemeine Beschreibung

Harmine hydrochloride is an alkaloid found in Peganum harmala.

Biochem./physiol. Wirkung

CNS stimulant.
Harmine hydrochloride has been considered for treatment of cancer and cerebral diseases and is a known CNS stimulant.

Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral - Carc. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Michael Tarpley et al.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 162, 105821-105821 (2021-03-31)
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Elisangela G Cata-Preta et al.
Frontiers in pharmacology, 9, 561-561 (2018-06-14)
Ayahuasca is a hallucinogenic beverage produced from the decoction of Banisteriopsis caapi (Bc) and Psychotria viridis (Pv), β-carboline- and N,N-dimethyltryptamine(DMT)-containing plants, respectively. Accumulating evidence suggests that ayahuasca may have therapeutic effects on ethanol abuse. It is not known, however, whether
Ronan Le Moigne et al.
Cells, 9(5) (2020-05-14)
Numerous studies have shown that alteration of actin remodeling plays a pivotal role in the regulation of morphologic and phenotypic changes leading to malignancy. In the present study, we searched for drugs that can regulate actin polymerization and reverse the
Armin Madadkar Sobhani et al.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques, 5(1), 19-23 (2002-06-04)
Peganum harmala L. (Zygophyllaceae) seeds extract is one of the main components of an ethnobotanical preparation used in the treatment of neoplasms in Iran. Cytotoxic effects of P. harmala extract on cancerous cell-lines have been reported before. beta-carbolines like harmaline
Xiuyun Li et al.
Frontiers in microbiology, 10, 2295-2295 (2019-11-22)
Several studies have demonstrated the significant antiviral, antimicrobial, antiplasmodial, antioxidative, antifungal, antimutagenic, and antitumor properties of harmine hydrochloride (HMH). The main objective of the present study was to investigate the antifungal effects and underlying mechanisms of HMH when combined with
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