SAB4504642

Anti-phospho-RIPK2 (pSer¹⁷⁶) antibody produced in rabbit

affinity isolated antibody

• Synonym(e): Anti-CARD3, Anti-CARDIAK, Anti-CCK, Anti-GIG30, Anti-RICK, Anti-RIP2
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 61 kDa
• Speziesreaktivität: mouse, rat, human
• Konzentration: ~1 mg/mL
• Methode(n): ELISA: 1:40000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• NCBI-Hinterlegungsnummer: O43353
• UniProt-Hinterlegungsnummer: O43353
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: phosphorylation (pSer176)
• Angaben zum Gen: human ... RIPK2(8767)

Beschreibung

Allgemeine Beschreibung

Receptor interacting protein kinase 2 (RIP2K) has an N-terminal dual-specificity ser/tyr kinase domain. This gene is a member of the TKL kinase family (tyrosine kinase-like). RIP2K is located on human chromosome 8q21.

Immunogen

The antiserum was produced against synthesized peptide derived from human RIPK2 around the phosphorylation site of Ser176.

Immunogen Range: 146-195

Biochem./physiol. Wirkung

Receptor interacting protein kinase 2 (RIP2K) can act as a new target for anti-inflammatory drugs. This gene participates in multiple nuclear factor-κB (NFκB) activation pathways and human colon tumorigenesis.

Leistungsmerkmale und Vorteile

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Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable