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Dokumente

SAB4504446

Sigma-Aldrich

Anti-phospho-JAK1 (pTyr1022) antibody produced in rabbit

affinity isolated antibody

Synonym(e):

Anti-AIIDE, Anti-JAK1A, Anti-JAK1B, Anti-JTK3

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 131 kDa

Speziesreaktivität

mouse, human, rat

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:10000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

P23458

UniProt-Hinterlegungsnummer

P23458

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

phosphorylation (pTyr1022)

Angaben zum Gen

human ... JAK1(3716)

Immunogen

The antiserum was produced against synthesized peptide derived from human JAK1 around the phosphorylation site of Tyr1022.

Immunogen Range: 988-1037

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Mari Ikai et al.
Veterinary dermatology, 34(4), 318-326 (2023-03-18)
Canine atopic dermatitis (cAD) is a disease associated with Type 2 helper T (Th2) immune responses in the acute phase of the disease. In humans, keratinocytes are activated by Th2 cytokines via the Janus kinase (JAK)/signal transducer and activator of
Takuwa Yasuda et al.
The Journal of clinical investigation, 126(6), 2064-2076 (2016-04-26)
Skin homeostasis is maintained by the continuous proliferation and differentiation of epidermal cells. The skin forms a strong but flexible barrier against microorganisms as well as physical and chemical insults; however, the physiological mechanisms that maintain this barrier are not
Hongnan Jiang et al.
Oncology reports, 48(5) (2022-10-01)
The present study aimed to investigate the underlying regulatory mechanism of MYCL proto‑oncogene (MYCL) in triple‑negative breast cancer (TNBC) progression. In vitro experiments were performed to confirm the functional roles of MYCL in TNBC, and its effects on the JAK/STAT3 pathway

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